Donor and transplant characteristics
Data . | No. . |
|---|---|
| Donor age, y, range (median) | 6-65 (39) |
| Donor sex, M/F | 31/25 |
| Relationship | |
| Related | 36 |
| HLA-identical sibling | 31 |
| HLA-nonidentical relative* | 5 |
| Unrelated | 20 |
| HLA-identical | 14 |
| HLA-nonidentical† | 6 |
| Source of stem cells | |
| Marrow | 33 |
| Peripheral blood | 23 |
| Conditioning regimen | |
| BUCY (targeted) | 44 (39) |
| BUTBI (1200) | 7 |
| CYTBI (1200) | 5 |
| GVHD prophylaxis | |
| MTX + CSP | 50 |
| MMF + CSP | 3 |
| MTX + FK506 | 2 |
| MTX | 1 |
| CMV status, patient/donor‡ | |
| +/+ | 10 |
| +/- | 10 |
| -/+ | 6 |
| -/- | 21 |
Data . | No. . |
|---|---|
| Donor age, y, range (median) | 6-65 (39) |
| Donor sex, M/F | 31/25 |
| Relationship | |
| Related | 36 |
| HLA-identical sibling | 31 |
| HLA-nonidentical relative* | 5 |
| Unrelated | 20 |
| HLA-identical | 14 |
| HLA-nonidentical† | 6 |
| Source of stem cells | |
| Marrow | 33 |
| Peripheral blood | 23 |
| Conditioning regimen | |
| BUCY (targeted) | 44 (39) |
| BUTBI (1200) | 7 |
| CYTBI (1200) | 5 |
| GVHD prophylaxis | |
| MTX + CSP | 50 |
| MMF + CSP | 3 |
| MTX + FK506 | 2 |
| MTX | 1 |
| CMV status, patient/donor‡ | |
| +/+ | 10 |
| +/- | 10 |
| -/+ | 6 |
| -/- | 21 |
BU indicates busulfan; TBI, total body irradiation (cGy); MTX, methotrexate; CSP, cyclosporine; MMF, mycophenolate mofetil; and FK506, tacrolimus.
Of the donors, 1 was HLA phenotypically matched; 2 were mismatched for HLA-B, 1 for DR, and 1 for DR and DQ
Of the donors, 2 were mismatched for DQB1, 1 each for HLA-A or HLA-B, and 2 for DR and DQ
In 9 patient/donor pairs, the information on CMV was incomplete