Patient and disease characteristics
Data . | No. . |
|---|---|
| Number of patients studied | 56 |
| Patient age, y, range (median) | 10-66 (43) |
| Patient sex, M/F | 28/28 |
| Disease duration, mo, range (median) | 3-312 (33) |
| Primary diagnosis | |
| IMF | 33 |
| ET with myelofibrosis | 10 |
| P vera with myelofibrosis | 5 |
| Myelofibrosis with increased blasts* | 5 |
| Other† | 3 |
| Degree of marrow fibrosis‡ | |
| 1 (mild) | 21 |
| 2 (moderate) | 17 |
| 3 (severe) | 18 |
| Dupriez classification at transplantation§ | |
| Good | 25 |
| Intermediate | 17 |
| Poor | 13 |
| Platelet count at transplantation¶ | |
| 100 × 109/L or higher | 40 |
| Less than 100 × 109/L | 15 |
| Prior splenectomy | |
| Yes/no | 20/36 |
Data . | No. . |
|---|---|
| Number of patients studied | 56 |
| Patient age, y, range (median) | 10-66 (43) |
| Patient sex, M/F | 28/28 |
| Disease duration, mo, range (median) | 3-312 (33) |
| Primary diagnosis | |
| IMF | 33 |
| ET with myelofibrosis | 10 |
| P vera with myelofibrosis | 5 |
| Myelofibrosis with increased blasts* | 5 |
| Other† | 3 |
| Degree of marrow fibrosis‡ | |
| 1 (mild) | 21 |
| 2 (moderate) | 17 |
| 3 (severe) | 18 |
| Dupriez classification at transplantation§ | |
| Good | 25 |
| Intermediate | 17 |
| Poor | 13 |
| Platelet count at transplantation¶ | |
| 100 × 109/L or higher | 40 |
| Less than 100 × 109/L | 15 |
| Prior splenectomy | |
| Yes/no | 20/36 |
IMF indicates idiopathic myelofibrosis; ET, essential thrombocythemia; and P vera, polycythemia vera.
All 5 patients had IMF
One patient had IMF that evolved to CML. There were 2 patients who had evidence of NHL in lymph nodes, suggesting the synchronous occurrence of 2 malignancies
According to Guardiola et al.13
Data were incomplete for one patient
Counts were not available for one patient