Table 2.

Best response to rituximab according to the primary site of lymphoma localization and previous chemotherapy in 34 evaluable patients


Response

No prior chemotherapy, n = 23

Prior chemotherapy, n = 11

Primary gastric site, n = 14*

Primary nongastric site, n = 20

All patients, n = 34
ORR (%)   20 (87)  5 (45)  9 (64)   16 (80)   25 (73)  
CR (%)   11 (48)   4 (36)   4 (29)   11 (55)   15 (44)  
PR (%)   9 (39)   1 (9)   5 (35)   5 (25)   10 (29)  
SD (%)   2 (9)   4 (36)   4 (29)   2 (10)   6 (18)  
PD (%)
 
1 (4)
 
2 (18)
 
1 (7)
 
2 (10)
 
3 (9)
 

Response

No prior chemotherapy, n = 23

Prior chemotherapy, n = 11

Primary gastric site, n = 14*

Primary nongastric site, n = 20

All patients, n = 34
ORR (%)   20 (87)  5 (45)  9 (64)   16 (80)   25 (73)  
CR (%)   11 (48)   4 (36)   4 (29)   11 (55)   15 (44)  
PR (%)   9 (39)   1 (9)   5 (35)   5 (25)   10 (29)  
SD (%)   2 (9)   4 (36)   4 (29)   2 (10)   6 (18)  
PD (%)
 
1 (4)
 
2 (18)
 
1 (7)
 
2 (10)
 
3 (9)
 
*

One patient with primary gastric disease did not complete the treatment and was not evaluable for response.

The difference in ORR between chemotherapy-naive and pretreated patients was statistically significant (2-sided Fisher exact test, P = .03).

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