Cytogenetic profile of patients
Patient . | Age, y/sex . | Diagnosis . | Karyotype . |
|---|---|---|---|
| 1 | 45/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10), add(10)(q?)[20] |
| 2 | 74/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[18] |
| 3 | 67/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[9]/46, XY[6] |
| 4 | 74/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10), del(20)(q11)[12]/45, idem,−20[4] |
| 5 | 66/M | MDS, MF | 46,XY, + 1,der(1;7) (q10;p10)[5]/47, idem, + 8[13] |
| 6* | 58/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[3]/46, XY[18] |
| 7* | 53/F | MDS | 46,XX, + 1,der(1;7) (q10;p10)[12]/46,X,−X, + 1,der(1;7)(q10;p10), + der(1;7)(q10;p10), −2, +5, +6, −8, −12, +14, −16, −17, +18, +21[1]/46, XX[7] |
| 8* | 70/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[18]/46, XY[2] |
| 9* | 67/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[1]/47, idem, + 82/20/46, idem, del(20)(q11)[2]/47, idem, + 8, del(20)(q11)[15] |
| 10 | 51/M | MDS (RAEB) | 46,XY, + 1,der(1;7) (q10;p10)[19]/45, X,−Y, idem[1] |
| 11 | 53/M | MDS | 46,XY, + 1,der(1;7) (q10;p10)[20] |
| 12 | 68/M | MDS | 46,XY, + 1,der(1;7) (q10;p10)[10]/46, XY[10] |
| 13 | 49/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[12]/46, XY[8] |
| 14 | 49/M | AML (M0) | 46,XY, + 1,der(1;7) (q10;p10)[20] |
| 15* | 68/M | AML (M2) | 46,XY, + 1,der(1;7) (q10;p10)[5]/47, idem, + 8[16] |
| 16 | 88/M | MDS (RA) | 47,XY, + 1,der(1;7) (q10;p10), del(20)(q?), del(20)[9]/46, XY[10] |
| 17 | 56/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[18]/46, XY[4] |
| 18* | 47/M | MF | 46,XY, + 1,der(1;7) (q10;p10)[16]/46, XY[2] |
| 19 | 58/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[3]/47, idem, + 8[16]/46, XY[2] |
| 20* | 74/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[13]/46, XY[1] |
| 21* | 68/M | MDS (RAEB-t) | 46,XY, + 1,der(1;7) (q10;p10)[14]/46, XY[6] |
| 22 | 54/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[2]/46, XY[18] |
| 23 | 72/M | MF | 46,XY, + 1,der(1;7) (q10;p10)[1]/46, XY,del(13)(q10q21)[4]/46, XY[14] |
| 24* | 57/M | MM | 46,XY, + 1,der(1;7) (q10;p10)[5]/46, XY[16] |
| 25* | 70/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[9] |
| 26 | 72/M | AML (M0) | 46,XY, + 1,der(1;7) (q10;p10)[17]/45, idem, −14[1]/45, idem, −21[1]/46, XY[1] |
| 27 | 58/M | MDS/AML | 47,XY, + 1,der(1;7) (q10;p10), + 8[4]/47, idem, del (20)(q11)[1]/46, XY[1] |
Patient . | Age, y/sex . | Diagnosis . | Karyotype . |
|---|---|---|---|
| 1 | 45/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10), add(10)(q?)[20] |
| 2 | 74/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[18] |
| 3 | 67/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[9]/46, XY[6] |
| 4 | 74/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10), del(20)(q11)[12]/45, idem,−20[4] |
| 5 | 66/M | MDS, MF | 46,XY, + 1,der(1;7) (q10;p10)[5]/47, idem, + 8[13] |
| 6* | 58/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[3]/46, XY[18] |
| 7* | 53/F | MDS | 46,XX, + 1,der(1;7) (q10;p10)[12]/46,X,−X, + 1,der(1;7)(q10;p10), + der(1;7)(q10;p10), −2, +5, +6, −8, −12, +14, −16, −17, +18, +21[1]/46, XX[7] |
| 8* | 70/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[18]/46, XY[2] |
| 9* | 67/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[1]/47, idem, + 82/20/46, idem, del(20)(q11)[2]/47, idem, + 8, del(20)(q11)[15] |
| 10 | 51/M | MDS (RAEB) | 46,XY, + 1,der(1;7) (q10;p10)[19]/45, X,−Y, idem[1] |
| 11 | 53/M | MDS | 46,XY, + 1,der(1;7) (q10;p10)[20] |
| 12 | 68/M | MDS | 46,XY, + 1,der(1;7) (q10;p10)[10]/46, XY[10] |
| 13 | 49/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[12]/46, XY[8] |
| 14 | 49/M | AML (M0) | 46,XY, + 1,der(1;7) (q10;p10)[20] |
| 15* | 68/M | AML (M2) | 46,XY, + 1,der(1;7) (q10;p10)[5]/47, idem, + 8[16] |
| 16 | 88/M | MDS (RA) | 47,XY, + 1,der(1;7) (q10;p10), del(20)(q?), del(20)[9]/46, XY[10] |
| 17 | 56/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[18]/46, XY[4] |
| 18* | 47/M | MF | 46,XY, + 1,der(1;7) (q10;p10)[16]/46, XY[2] |
| 19 | 58/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[3]/47, idem, + 8[16]/46, XY[2] |
| 20* | 74/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[13]/46, XY[1] |
| 21* | 68/M | MDS (RAEB-t) | 46,XY, + 1,der(1;7) (q10;p10)[14]/46, XY[6] |
| 22 | 54/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[2]/46, XY[18] |
| 23 | 72/M | MF | 46,XY, + 1,der(1;7) (q10;p10)[1]/46, XY,del(13)(q10q21)[4]/46, XY[14] |
| 24* | 57/M | MM | 46,XY, + 1,der(1;7) (q10;p10)[5]/46, XY[16] |
| 25* | 70/M | MDS (RA) | 46,XY, + 1,der(1;7) (q10;p10)[9] |
| 26 | 72/M | AML (M0) | 46,XY, + 1,der(1;7) (q10;p10)[17]/45, idem, −14[1]/45, idem, −21[1]/46, XY[1] |
| 27 | 58/M | MDS/AML | 47,XY, + 1,der(1;7) (q10;p10), + 8[4]/47, idem, del (20)(q11)[1]/46, XY[1] |
RA indicates refractory anemia; MF, myelofibrosis; RAEB, refractory anemia with excess blasts; M0, minimally differentiated acute myeloblastic leukemia; M2, acute myeloblastic leukemia with maturation; RAEB-t, refractory anemia with excess blasts in transformation; and MM, multiple myeloma.
Therapy-related cases.