NF-κB activity does not contribute to tal-1-induced tumor growth
tal-1 tumor line . | No. of mice developing tumors . | Average tumor size, cm . |
|---|---|---|
| 5721 | 2/2 | 2.5 |
| 5721 lck-IκBα RR-AA | 2/2 | 2.75 |
| 1326 | 2/2 | 2.5 |
| 1326 lck-IκBα RR-AA | 1/1 | 3 |
| 5146 | 2/2 | 3.75 |
| 5146 lck-IκBα RR-AA | 3/3 | 3.25 |
tal-1 tumor line . | No. of mice developing tumors . | Average tumor size, cm . |
|---|---|---|
| 5721 | 2/2 | 2.5 |
| 5721 lck-IκBα RR-AA | 2/2 | 2.75 |
| 1326 | 2/2 | 2.5 |
| 1326 lck-IκBα RR-AA | 1/1 | 3 |
| 5146 | 2/2 | 3.75 |
| 5146 lck-IκBα RR-AA | 3/3 | 3.25 |
Syngeneic mice were injected intraperitoneally with 5 million tumor cells. All animals displayed evidence of disease and were killed 6 weeks after the cells were injected.