Table 1. Percentage of KO cells in... | American Society of Hematology

Table 1.

Percentage of KO cells in G-CSFR KO/WT chimeras

Chimera, KO/WT^*	B-lymphocytes, % KO (KO/WT ratio)†	Blood, % KO (KO/WT ratio)†					Bone marrow neutrophils, % KO (KO/WT ratio)†
Chimera, KO/WT^*	B-lymphocytes, % KO (KO/WT ratio)†			T lymphocytes	Neutrophils	Monocytes	Bone marrow neutrophils, % KO (KO/WT ratio)†
1:1	57 ± 11 (1.4:1)	53 ± 7 (1.2:1)	2 ± 1 (0.02:1)	ND	4 ± 1 (0.04:1)
3:1	76 ± 10 (3.0:1)	68 ± 9 (2.4:1)	4 ± 2 (0.04:1)	ND	7 ± 2 (0.08:1)
9:1	83 ± 4 (4.9:1)	79 ± 6 (4.2:1)	8 ± 5 (0.09:1)	34 ± 12 (0.6:1)	17 ± 8 (0.2:1)

Chimera, KO/WT^*	B-lymphocytes, % KO (KO/WT ratio)†	Blood, % KO (KO/WT ratio)†					Bone marrow neutrophils, % KO (KO/WT ratio)†
Chimera, KO/WT^*	B-lymphocytes, % KO (KO/WT ratio)†			T lymphocytes	Neutrophils	Monocytes	Bone marrow neutrophils, % KO (KO/WT ratio)†
1:1	57 ± 11 (1.4:1)	53 ± 7 (1.2:1)	2 ± 1 (0.02:1)	ND	4 ± 1 (0.04:1)
3:1	76 ± 10 (3.0:1)	68 ± 9 (2.4:1)	4 ± 2 (0.04:1)	ND	7 ± 2 (0.08:1)
9:1	83 ± 4 (4.9:1)	79 ± 6 (4.2:1)	8 ± 5 (0.09:1)	34 ± 12 (0.6:1)	17 ± 8 (0.2:1)

ND indicates not determined.

The original transplant ratio.

†

The percentage of KO cells in each lineage at 6 months after transplantation (n = 6 minimum, each). Data represent the mean ± SD, followed by the calculated KO/WT ratio after transplantation.

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