Table 7.

Expression of BCL6, MUM1, and CD138 in monoclonal B-cell PTLDs


Histology

BCL6+/MUM1−/+/CD138 positive/tested (%)

BCL6/MUM1+/CD138 positive/tested (%)

BCL6/MUM1+/CD138+ positive/tested (%)

BCL6/MUM1/CD138 positive/tested (%)
All PTLDs   10/44 (22.7)   18/44 (40.9)   13/44 (29.5)   3/44 (6.82)  
P-PTLD   0/12   8/12 (66.7)   3/12 (25.0)   1/12 (8.33)  
DLBCL (all variants)   10/32 (31.2)   10/32 (31.2)   10/32 (31.2)   2/32 (6.25)  
DLBCL, centroblastic   10/14 (71.4)*  1/14 (7.14)   1/14 (7.14)   2/14 (14.3)  
DLBCL, immunoblastic   0/15   7/15 (46.7)   8/15 (53.3)   0/15  
DLBCL, anaplastic
 
0/3
 
2/3 (66.7)
 
1/3 (33.3)
 
0/3
 

Histology

BCL6+/MUM1−/+/CD138 positive/tested (%)

BCL6/MUM1+/CD138 positive/tested (%)

BCL6/MUM1+/CD138+ positive/tested (%)

BCL6/MUM1/CD138 positive/tested (%)
All PTLDs   10/44 (22.7)   18/44 (40.9)   13/44 (29.5)   3/44 (6.82)  
P-PTLD   0/12   8/12 (66.7)   3/12 (25.0)   1/12 (8.33)  
DLBCL (all variants)   10/32 (31.2)   10/32 (31.2)   10/32 (31.2)   2/32 (6.25)  
DLBCL, centroblastic   10/14 (71.4)*  1/14 (7.14)   1/14 (7.14)   2/14 (14.3)  
DLBCL, immunoblastic   0/15   7/15 (46.7)   8/15 (53.3)   0/15  
DLBCL, anaplastic
 
0/3
 
2/3 (66.7)
 
1/3 (33.3)
 
0/3
 

P-PTLD indicates polymorphic PTLD; DLBCL, diffuse large B-cell lymphoma; and BL/BLL, Burkitt lymphoma/Burkitt-like lymphoma.

*

Of the cases, 8 displayed the BCL6+/MUM1/CD138 phenotype and 2 displayed the BCL6+/MUM1+/CD138 phenotype.

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