Expression of BCL6, MUM1, and CD138 in monoclonal B-cell PTLDs
Histology . | BCL6+/MUM1−/+/CD138− positive/tested (%) . | BCL6−/MUM1+/CD138− positive/tested (%) . | BCL6−/MUM1+/CD138+ positive/tested (%) . | BCL6−/MUM1−/CD138− positive/tested (%) . |
---|---|---|---|---|
All PTLDs | 10/44 (22.7) | 18/44 (40.9) | 13/44 (29.5) | 3/44 (6.82) |
P-PTLD | 0/12 | 8/12 (66.7) | 3/12 (25.0) | 1/12 (8.33) |
DLBCL (all variants) | 10/32 (31.2) | 10/32 (31.2) | 10/32 (31.2) | 2/32 (6.25) |
DLBCL, centroblastic | 10/14 (71.4)* | 1/14 (7.14) | 1/14 (7.14) | 2/14 (14.3) |
DLBCL, immunoblastic | 0/15 | 7/15 (46.7) | 8/15 (53.3) | 0/15 |
DLBCL, anaplastic | 0/3 | 2/3 (66.7) | 1/3 (33.3) | 0/3 |
Histology . | BCL6+/MUM1−/+/CD138− positive/tested (%) . | BCL6−/MUM1+/CD138− positive/tested (%) . | BCL6−/MUM1+/CD138+ positive/tested (%) . | BCL6−/MUM1−/CD138− positive/tested (%) . |
---|---|---|---|---|
All PTLDs | 10/44 (22.7) | 18/44 (40.9) | 13/44 (29.5) | 3/44 (6.82) |
P-PTLD | 0/12 | 8/12 (66.7) | 3/12 (25.0) | 1/12 (8.33) |
DLBCL (all variants) | 10/32 (31.2) | 10/32 (31.2) | 10/32 (31.2) | 2/32 (6.25) |
DLBCL, centroblastic | 10/14 (71.4)* | 1/14 (7.14) | 1/14 (7.14) | 2/14 (14.3) |
DLBCL, immunoblastic | 0/15 | 7/15 (46.7) | 8/15 (53.3) | 0/15 |
DLBCL, anaplastic | 0/3 | 2/3 (66.7) | 1/3 (33.3) | 0/3 |
P-PTLD indicates polymorphic PTLD; DLBCL, diffuse large B-cell lymphoma; and BL/BLL, Burkitt lymphoma/Burkitt-like lymphoma.
Of the cases, 8 displayed the BCL6+/MUM1−/CD138− phenotype and 2 displayed the BCL6+/MUM1+/CD138− phenotype.