Table 2. Body weight changes by strain... | American Society of Hematology

Table 2.

Body weight changes by strain in chronically DOX-treated mice (total cumulative dose, 30 mg/kg)

	Body weight, g
Treatment	Initial	Terminal
Wild-type
Saline	20.8 ± 2.3	26.3 ± 4.0
DOX
Survivors	21.3 ± 0.8	25.2 ± 4.5
Nonsurvivors	20.4 ± 2.2	18.4 ± 0.6^*
Hfe^+/−
Saline	20.3 ± 2.2	24.8 ± 2.0
DOX
Survivors	21.8 ± 2.4	22.2 ± 1.5^*†
Nonsurvivors	21.3 ± 2.3	17.0 ± 1.3^*
Hfe^−/−
Saline	19.6 ± 1.9	24.3 ± 3.2
DOX
Survivors	19.9 ± 1.1	21.2 ± 1.9^*†
Nonsurvivors	20.0 ± 1.4	17.8 ± 2.0^*

	Body weight, g
Treatment	Initial	Terminal
Wild-type
Saline	20.8 ± 2.3	26.3 ± 4.0
DOX
Survivors	21.3 ± 0.8	25.2 ± 4.5
Nonsurvivors	20.4 ± 2.2	18.4 ± 0.6^*
Hfe^+/−
Saline	20.3 ± 2.2	24.8 ± 2.0
DOX
Survivors	21.8 ± 2.4	22.2 ± 1.5^*†
Nonsurvivors	21.3 ± 2.3	17.0 ± 1.3^*
Hfe^−/−
Saline	19.6 ± 1.9	24.3 ± 3.2
DOX
Survivors	19.9 ± 1.1	21.2 ± 1.9^*†
Nonsurvivors	20.0 ± 1.4	17.8 ± 2.0^*

Data are presented as means ± SD.

P < .05, comparison between saline-treated and DOX-treated mice.

P < .05, comparison between wild-type and mutant mice with the same treatment.