Table 1. Serum iron (SI), total iron... | American Society of Hematology

Table 1.

Serum iron (SI), total iron binding capacity (TIBC), and transferrin saturation (TS) by strain on day 4 after a single DOX injection (20 mg/kg)

Treatment	SI, μM	TIBC, μM	TS, %
Wild-type
Saline	24.8 ± 7.1	43.2 ± 4.1	58.1 ± 18.7
DOX	42.4 ± 8.1^*	45.9 ± 3.7	92.8 ± 18.2^*
*Hfe*^-/-
Saline	41.7 ± 5.8†	42.1 ± 5.9	100.4 ± 13.3†
DOX	50.1 ± 8.1^*	51.0 ± 7.4^*	106.0 ± 6.0

Treatment	SI, μM	TIBC, μM	TS, %
Wild-type
Saline	24.8 ± 7.1	43.2 ± 4.1	58.1 ± 18.7
DOX	42.4 ± 8.1^*	45.9 ± 3.7	92.8 ± 18.2^*
*Hfe*^-/-
Saline	41.7 ± 5.8†	42.1 ± 5.9	100.4 ± 13.3†
DOX	50.1 ± 8.1^*	51.0 ± 7.4^*	106.0 ± 6.0

Data are presented as means ± SD.

P < .05, comparison between saline-treated and DOX-treated mice (n = 7-8 per group).

P < .05, comparison between wild-type and mutant mice with the same treatment.