Demographic and clinical characteristics of 52 hemophilia patients with inhibitors
Variable . | Value . |
|---|---|
| Age, y | |
| Mean (± SD) | 36.1 (± 11.9) |
| Median (min-max) | 34.8 (15-64) |
| Frequency | |
| Hemophilia A, % | 100 |
| Severe hemophilia, % | 94.2 |
| Inhibitors | |
| Frequency of high (> 5 BU) responders, % | 98.0* |
| Maximum inhibitor titer in high responders, median (min-max) | 100 (6-9999) |
| Frequency, % | |
| HIV infection | 7.8 |
| HBV infection | 23.5 |
| HCV infection | 86.3 |
| Disability | |
| Patients with hemophilia-related disability, % | 80.8 |
| Severity of disability, %, median (min-max) | 80.0 (40-100) |
| Orthopedic functioning† | |
| Median orthopedic joint score (min-max) | 9.0 (0-29) |
| Patients with chronic synovitis, % | 26.9 |
Variable . | Value . |
|---|---|
| Age, y | |
| Mean (± SD) | 36.1 (± 11.9) |
| Median (min-max) | 34.8 (15-64) |
| Frequency | |
| Hemophilia A, % | 100 |
| Severe hemophilia, % | 94.2 |
| Inhibitors | |
| Frequency of high (> 5 BU) responders, % | 98.0* |
| Maximum inhibitor titer in high responders, median (min-max) | 100 (6-9999) |
| Frequency, % | |
| HIV infection | 7.8 |
| HBV infection | 23.5 |
| HCV infection | 86.3 |
| Disability | |
| Patients with hemophilia-related disability, % | 80.8 |
| Severity of disability, %, median (min-max) | 80.0 (40-100) |
| Orthopedic functioning† | |
| Median orthopedic joint score (min-max) | 9.0 (0-29) |
| Patients with chronic synovitis, % | 26.9 |