Transcripts of NK-cell antigen receptors in lymphoblastic lymphomas and peripheral T-cell lymphomas
Case no. . | Sex . | Age, y . | TCR . | CD3m . | CD56 . | 2dl4 . | 2d . | 3d . | CD94 . | 2A . | 2C . | 2D . | 2F . | LDH, IU/L . | WBC, 103/μL . | HB, g/dL . | PLT, 103/μL . | Stage . | Tx . | PF . | Course . | Sur . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LBL | ||||||||||||||||||||||
| CD3m− | ||||||||||||||||||||||
| 1 | M | 39 | − | − | − | − | + | + | + | + | − | − | − | 908 | 5.6 | 14.1 | 313 | IV | C + B | N | Died of CMV 7 mo later | 7 |
| 2 | M | 9 | − | − | − | − | − | + | − | + | − | − | − | 540 | 2.8 | 8.2 | 125 | IV | C + B | Y | CR for 34 mo | 36+ |
| 3 | F | 19 | − | − | − | + | − | + | + | + | − | − | − | 247 | 9.1 | 13.3 | 129 | IV | C | Y | CR for 56 mo | 56+ |
| 4 | F | 28 | − | − | − | + | − | + | + | + | − | − | − | 318 | 6.6 | 10.6 | 266 | IV | C + B | Y | CR for 32 mo | 32+ |
| 5 | M | 14 | + | − | − | − | − | − | − | − | − | − | + | 269 | 4.8 | 7.8 | 49 | IV | C | N | Died 2 mo later | 2 |
| 6 | F | 69 | + | − | − | − | − | − | − | − | − | − | − | 373 | 7.6 | 3.5 | 52 | III | C | N | Died 5 mo later | 5 |
| CD3m+ | ||||||||||||||||||||||
| 1 | F | 7 | + | + | − | − | − | − | − | − | − | − | − | 494 | 7.1 | 12.4 | 255 | III | C | N | Died 12 mo later | 12 |
| 2 | M | 15 | + | + | − | − | − | − | − | − | − | − | − | 2353 | 15.3 | 12.2 | 92 | IV | C + B | Y | CR for 27 mo | 27+ |
| 3 | M | 16 | + | + | − | − | − | − | − | − | − | − | − | 459 | 1.5 | 8.8 | 200 | III | C + B | Y | CR for 43 mo | 43+ |
| PTCL | ||||||||||||||||||||||
| 1 | M | 35 | + | + | − | − | − | − | − | − | − | − | − | WNL | WNL | WNL | WNL | III | C + B | N | CR for 6 mo, recurred, died after BMT | 30 |
| 2 | M | 70 | + | + | − | + | − | − | − | − | − | − | − | 1477 | 22.3 | 8.1 | 33 | I | C | N | Died of sepsis during induction | 1 |
| 3 | F | 33 | + | + | − | − | − | − | − | − | − | − | − | 710 | 4.5 | 11.9 | 177 | IV | C | N | Died of multiorgan failure during induction | 2 |
| 4 | M | 41 | + | + | − | − | − | − | − | − | − | − | − | 612 | 3.9 | 11.7 | 197 | III | C + B | Y | CR for 2 y | 24+ |
| 5 | M | 63 | + | + | − | − | − | − | − | − | − | − | − | 1437 | 103.9 | 13.5 | 210 | IV | C | N | Transient response, died of septic shock | 3 |
| 6 | F | 68 | + | + | − | − | − | − | − | − | − | − | − | 634 | 2.2 | 7.2 | 51 | IV | C | N | Died of pneumonia during induction | 1 |
| 7 | M | 43 | + | + | − | − | − | − | − | − | − | − | − | ND | 2.6 | 7.3 | 22 | I | C | N | CR for 2 y, recurred and died 6 mo later | 32 |
| 8 | F | 77 | + | + | − | − | − | − | + | − | − | − | − | WNL | WNL | WNL | WNL | II | C | Y | CR for 5 y | 72+ |
| 9 | F | 68 | + | + | − | − | − | − | − | − | − | − | − | 2202 | 11.4 | 10.4 | 115 | III | C | N | Progression despite C/T, died | 8 |
| 10 | F | 66 | + | + | − | − | − | − | − | − | − | − | − | 517 | 4.2 | 9.1 | 154 | IV | C | N | Interrupted C/T, loss to follow-up 22 mo later | 22+ |
Case no. . | Sex . | Age, y . | TCR . | CD3m . | CD56 . | 2dl4 . | 2d . | 3d . | CD94 . | 2A . | 2C . | 2D . | 2F . | LDH, IU/L . | WBC, 103/μL . | HB, g/dL . | PLT, 103/μL . | Stage . | Tx . | PF . | Course . | Sur . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LBL | ||||||||||||||||||||||
| CD3m− | ||||||||||||||||||||||
| 1 | M | 39 | − | − | − | − | + | + | + | + | − | − | − | 908 | 5.6 | 14.1 | 313 | IV | C + B | N | Died of CMV 7 mo later | 7 |
| 2 | M | 9 | − | − | − | − | − | + | − | + | − | − | − | 540 | 2.8 | 8.2 | 125 | IV | C + B | Y | CR for 34 mo | 36+ |
| 3 | F | 19 | − | − | − | + | − | + | + | + | − | − | − | 247 | 9.1 | 13.3 | 129 | IV | C | Y | CR for 56 mo | 56+ |
| 4 | F | 28 | − | − | − | + | − | + | + | + | − | − | − | 318 | 6.6 | 10.6 | 266 | IV | C + B | Y | CR for 32 mo | 32+ |
| 5 | M | 14 | + | − | − | − | − | − | − | − | − | − | + | 269 | 4.8 | 7.8 | 49 | IV | C | N | Died 2 mo later | 2 |
| 6 | F | 69 | + | − | − | − | − | − | − | − | − | − | − | 373 | 7.6 | 3.5 | 52 | III | C | N | Died 5 mo later | 5 |
| CD3m+ | ||||||||||||||||||||||
| 1 | F | 7 | + | + | − | − | − | − | − | − | − | − | − | 494 | 7.1 | 12.4 | 255 | III | C | N | Died 12 mo later | 12 |
| 2 | M | 15 | + | + | − | − | − | − | − | − | − | − | − | 2353 | 15.3 | 12.2 | 92 | IV | C + B | Y | CR for 27 mo | 27+ |
| 3 | M | 16 | + | + | − | − | − | − | − | − | − | − | − | 459 | 1.5 | 8.8 | 200 | III | C + B | Y | CR for 43 mo | 43+ |
| PTCL | ||||||||||||||||||||||
| 1 | M | 35 | + | + | − | − | − | − | − | − | − | − | − | WNL | WNL | WNL | WNL | III | C + B | N | CR for 6 mo, recurred, died after BMT | 30 |
| 2 | M | 70 | + | + | − | + | − | − | − | − | − | − | − | 1477 | 22.3 | 8.1 | 33 | I | C | N | Died of sepsis during induction | 1 |
| 3 | F | 33 | + | + | − | − | − | − | − | − | − | − | − | 710 | 4.5 | 11.9 | 177 | IV | C | N | Died of multiorgan failure during induction | 2 |
| 4 | M | 41 | + | + | − | − | − | − | − | − | − | − | − | 612 | 3.9 | 11.7 | 197 | III | C + B | Y | CR for 2 y | 24+ |
| 5 | M | 63 | + | + | − | − | − | − | − | − | − | − | − | 1437 | 103.9 | 13.5 | 210 | IV | C | N | Transient response, died of septic shock | 3 |
| 6 | F | 68 | + | + | − | − | − | − | − | − | − | − | − | 634 | 2.2 | 7.2 | 51 | IV | C | N | Died of pneumonia during induction | 1 |
| 7 | M | 43 | + | + | − | − | − | − | − | − | − | − | − | ND | 2.6 | 7.3 | 22 | I | C | N | CR for 2 y, recurred and died 6 mo later | 32 |
| 8 | F | 77 | + | + | − | − | − | − | + | − | − | − | − | WNL | WNL | WNL | WNL | II | C | Y | CR for 5 y | 72+ |
| 9 | F | 68 | + | + | − | − | − | − | − | − | − | − | − | 2202 | 11.4 | 10.4 | 115 | III | C | N | Progression despite C/T, died | 8 |
| 10 | F | 66 | + | + | − | − | − | − | − | − | − | − | − | 517 | 4.2 | 9.1 | 154 | IV | C | N | Interrupted C/T, loss to follow-up 22 mo later | 22+ |
See footnote to Table 1 for abbreviations.