Table 1.

Baseline characteristics of study and reference patients with FL undergoing high-dose therapy and ASCT



HD-RIT, n = 27

C-HDT, n = 98

Characteristic
No.
%
No.
%
P
Bulk at Tx      
Less than 5 cm   19   70   77   79   .1  
5 cm or more   8   30   14   14   
Unknown   0   0   7   7   
Male sex   15   56   61   62   .53  
Median age, y (range)   46 (24-59)    49 (30-59)    .06  
Stages III/IV at Tx   26   96   89   91   .35  
LDH at Tx      
Elevated   11   41   17   17   .03  
Normal   16   59   69   70   
Unknown   0    12   12   
Age-adjusted IPI score      
0   1   4   8   8   
1   15   56   62   63   .019  
2   11   41   16   16   (0-1 vs 2-3)  
3   0   0   0   0   
Unknown     12   12   
Transformed to DLBCL   4   15   8   8   .3  
Documented splenomegaly   7   26   14   14   .15  
Median no. prior regimens   2(1-6)    2(1-11)    
  mean = 2.85    mean = 2.32    
3 or more prior regimens   13   48   33   34   .17  
Prior anthracycline   20   74   86   87   .08  
Prior platinum   10   37   34   35   .82  
Prior radiation   2   7   19   19   .24  
Chemosensitive disease   16   59   66   67   .57  
Chemoresistant/primary refractory at Tx   2   7   13   13   
Untreated relapse at Tx
 
9
 
33
 
19
 
19
 

 


HD-RIT, n = 27

C-HDT, n = 98

Characteristic
No.
%
No.
%
P
Bulk at Tx      
Less than 5 cm   19   70   77   79   .1  
5 cm or more   8   30   14   14   
Unknown   0   0   7   7   
Male sex   15   56   61   62   .53  
Median age, y (range)   46 (24-59)    49 (30-59)    .06  
Stages III/IV at Tx   26   96   89   91   .35  
LDH at Tx      
Elevated   11   41   17   17   .03  
Normal   16   59   69   70   
Unknown   0    12   12   
Age-adjusted IPI score      
0   1   4   8   8   
1   15   56   62   63   .019  
2   11   41   16   16   (0-1 vs 2-3)  
3   0   0   0   0   
Unknown     12   12   
Transformed to DLBCL   4   15   8   8   .3  
Documented splenomegaly   7   26   14   14   .15  
Median no. prior regimens   2(1-6)    2(1-11)    
  mean = 2.85    mean = 2.32    
3 or more prior regimens   13   48   33   34   .17  
Prior anthracycline   20   74   86   87   .08  
Prior platinum   10   37   34   35   .82  
Prior radiation   2   7   19   19   .24  
Chemosensitive disease   16   59   66   67   .57  
Chemoresistant/primary refractory at Tx   2   7   13   13   
Untreated relapse at Tx
 
9
 
33
 
19
 
19
 

 

Tx indicates transplantation; DLBCL, diffuse large B-cell lymphoma.

Close Modal

or Create an Account

Close Modal
Close Modal