Multivariate analysis of treatment-related mortality
Variables . | Relative risk of treatment-related mortality (95% CI) . | P . |
|---|---|---|
| Type of transplant* | < .001† | |
| Autologous unpurged, n = 596 | 1.00 | — |
| Autologous purged, n = 130 | 0.98 (0.52-1.87) | .96 |
| Allogeneic, n = 175 | 4.44 (2.81-7.02) | < .001 |
| Chemosensitivity | < .001† | |
| Sensitive, n = 714 | 1.00 | — |
| Resistant, n = 111 | 2.71 (1.69-4.36) | < .001 |
| Untreated/unknown, n = 76 | 1.78 (0.99-3.19) | .06 |
| Serum LDH at transplantation | < .001† | |
| Normal, n = 561 | 1.00 | — |
| Abnormal, n = 243 | 2.03 (1.32-3.14) | .001 |
| Unknown, n = 97 | 2.69 (1.43-5.04) | .002 |
| Age at transplantation | — | |
| No older than 40 y, n = 198 | 1.00 | — |
| Older than 40 y, n = 703 | 1.98 (1.21-3.26) | .007 |
| Conditioning regimen | ||
| Non-TBI, n = 553 | 1.00 | — |
| TBI, n = 348 | 1.80 (1.16-2.77) | .008 |
| Year of transplantation | .03† | |
| 1990-1993, n = 300 | 1.00 | — |
| 1994-1996, n = 373 | 0.67 (0.42-1.06) | .09 |
| 1997-1998, n = 228 | 0.49 (0.28-0.87) | .01 |
Variables . | Relative risk of treatment-related mortality (95% CI) . | P . |
|---|---|---|
| Type of transplant* | < .001† | |
| Autologous unpurged, n = 596 | 1.00 | — |
| Autologous purged, n = 130 | 0.98 (0.52-1.87) | .96 |
| Allogeneic, n = 175 | 4.44 (2.81-7.02) | < .001 |
| Chemosensitivity | < .001† | |
| Sensitive, n = 714 | 1.00 | — |
| Resistant, n = 111 | 2.71 (1.69-4.36) | < .001 |
| Untreated/unknown, n = 76 | 1.78 (0.99-3.19) | .06 |
| Serum LDH at transplantation | < .001† | |
| Normal, n = 561 | 1.00 | — |
| Abnormal, n = 243 | 2.03 (1.32-3.14) | .001 |
| Unknown, n = 97 | 2.69 (1.43-5.04) | .002 |
| Age at transplantation | — | |
| No older than 40 y, n = 198 | 1.00 | — |
| Older than 40 y, n = 703 | 1.98 (1.21-3.26) | .007 |
| Conditioning regimen | ||
| Non-TBI, n = 553 | 1.00 | — |
| TBI, n = 348 | 1.80 (1.16-2.77) | .008 |
| Year of transplantation | .03† | |
| 1990-1993, n = 300 | 1.00 | — |
| 1994-1996, n = 373 | 0.67 (0.42-1.06) | .09 |
| 1997-1998, n = 228 | 0.49 (0.28-0.87) | .01 |