Table 1. Cardiovascular parameters in 4-... | American Society of Hematology

Table 1.

Cardiovascular parameters in 4- to 7-month-old wild-type (wt), transgenic (tg), and splenectomized tg mice

	wt	tg	Splenectomized tg
n	11	13	8
Mean arterial blood pressure (mmHg)	99 ± 12	100 ± 7	110 ± 11
Heart rate (min^-1)	548 ± 44	573 ± 31	559 ± 39
Cardiac output (mL/min)*	17.2 ± 3.2	14.5 ± 6.9	16.5 ± 5.2
Central venous pressure (mmHg)	3.9 ± 0.8	6.6 ± 0.9†	5.2 ± 1.3‡

	wt	tg	Splenectomized tg
n	11	13	8
Mean arterial blood pressure (mmHg)	99 ± 12	100 ± 7	110 ± 11
Heart rate (min^-1)	548 ± 44	573 ± 31	559 ± 39
Cardiac output (mL/min)*	17.2 ± 3.2	14.5 ± 6.9	16.5 ± 5.2
Central venous pressure (mmHg)	3.9 ± 0.8	6.6 ± 0.9†	5.2 ± 1.3‡

Values are given as means plus or minus standard deviations.

Cardiac output was measured invasively in conscious as well as in halothane-anesthetized mice.

P < .01 versus wt.

P < .05 versus wt; P < .01 versus tg6.