Table 1. HO-1 mRNA expressions and HO... | American Society of Hematology

Table 1.

HO-1 mRNA expressions and HO activities induced by H₂O₂ in LCLs

					HO-1 mRNA expression*			HO-1 activity, nmol/mg/h*
Subject	Genotype	Age, y	Sex	(GT)n repeats	Baseline	After H₂O₂ treatment	Baseline	After H₂O₂ treatment
SS-1	S/S	64	Male	22/23	0.89 ± 0.02	1.61 ± 0.09†	0.48 ± 0.18	1.12 ± 0.09†
SS-2	S/S	66	Male	16/23	0.74 ± 0.03	1.90 ± 0.09†	0.69 ± 0.14	2.04 ± 0.58†
SS-3	S/S	77	Male	22/23	0.63 ± 0.07	0.94 ± 0.08†	1.52 ± 0.82	2.28 ± 1.45†
SS-4	S/S	24	Female	24/25	0.59 ± 0.01	1.33 ± 0.05†	1.50 ± 0.30	3.22 ± 0.46†
SS-5	S/S	38	Male	24/26	0.94 ± 0.20	2.63 ± 0.13†	1.32 ± 0.31	3.06 ± 0.51†
SS-6	S/S	43	Male	23/24	0.72 ± 0.04	1.39 ± 0.07†	1.29 ± 0.44	4.05 ± 1.40†
LL-1	L/L	62	Male	33/34	0.78 ± 0.08	0.80 ± 0.04	1.20 ± 0.64	1.02 ± 0.37
LL-2	L/L	58	Male	33/38	0.73 ± 0.29	0.84 ± 0.36	0.71 ± 0.38	0.57 ± 0.19
LL-3	L/L	68	Male	33/38	0.85 ± 0.09	0.79 ± 0.03	1.30 ± 1.00	1.41 ± 0.66
LL-4	L/L	24	Male	34/37	0.90 ± 0.01	0.88 ± 0.04	1.64 ± 0.33	1.96 ± 0.83
LL-5	L/L	70	Male	34/36	0.77 ± 0.09	0.89 ± 0.11	1.46 ± 0.39	1.50 ± 0.47
LL-6	L/L	31	Male	34/40	0.80 ± 0.34	0.89 ± 0.06	1.31 ± 0.04	1.61 ± 0.30

					HO-1 mRNA expression*			HO-1 activity, nmol/mg/h*
Subject	Genotype	Age, y	Sex	(GT)n repeats	Baseline	After H₂O₂ treatment	Baseline	After H₂O₂ treatment
SS-1	S/S	64	Male	22/23	0.89 ± 0.02	1.61 ± 0.09†	0.48 ± 0.18	1.12 ± 0.09†
SS-2	S/S	66	Male	16/23	0.74 ± 0.03	1.90 ± 0.09†	0.69 ± 0.14	2.04 ± 0.58†
SS-3	S/S	77	Male	22/23	0.63 ± 0.07	0.94 ± 0.08†	1.52 ± 0.82	2.28 ± 1.45†
SS-4	S/S	24	Female	24/25	0.59 ± 0.01	1.33 ± 0.05†	1.50 ± 0.30	3.22 ± 0.46†
SS-5	S/S	38	Male	24/26	0.94 ± 0.20	2.63 ± 0.13†	1.32 ± 0.31	3.06 ± 0.51†
SS-6	S/S	43	Male	23/24	0.72 ± 0.04	1.39 ± 0.07†	1.29 ± 0.44	4.05 ± 1.40†
LL-1	L/L	62	Male	33/34	0.78 ± 0.08	0.80 ± 0.04	1.20 ± 0.64	1.02 ± 0.37
LL-2	L/L	58	Male	33/38	0.73 ± 0.29	0.84 ± 0.36	0.71 ± 0.38	0.57 ± 0.19
LL-3	L/L	68	Male	33/38	0.85 ± 0.09	0.79 ± 0.03	1.30 ± 1.00	1.41 ± 0.66
LL-4	L/L	24	Male	34/37	0.90 ± 0.01	0.88 ± 0.04	1.64 ± 0.33	1.96 ± 0.83
LL-5	L/L	70	Male	34/36	0.77 ± 0.09	0.89 ± 0.11	1.46 ± 0.39	1.50 ± 0.47
LL-6	L/L	31	Male	34/40	0.80 ± 0.34	0.89 ± 0.06	1.31 ± 0.04	1.61 ± 0.30

Results are reported as means ± SDs among 5 lymphoblastoid cell clones from each subject.

Significantly greater than baseline value, P < .05.