Table 3.

Responses to therapy


Response

After CHOP, n (%)

After CHOP + tositumomab/iodine I 131 tositumomab,* n (%)
Complete remission   24 (27)   49 (54)  
Complete remission, unconfirmed   11 (12)   11 (12)  
Partial remission   44 (49)   21 (23)  
Stable disease   2 (2)   2 (2)* 
Not evaluable  9 (10)   7 (8)  
Total
 
90 (100)
 
90 (100)
 

Response

After CHOP, n (%)

After CHOP + tositumomab/iodine I 131 tositumomab,* n (%)
Complete remission   24 (27)   49 (54)  
Complete remission, unconfirmed   11 (12)   11 (12)  
Partial remission   44 (49)   21 (23)  
Stable disease   2 (2)   2 (2)* 
Not evaluable  9 (10)   7 (8)  
Total
 
90 (100)
 
90 (100)
 
*

Patients who did not achieve a PR, CRu, or CR with CHOP were not eligible to receive tositumomab/iodine I 131 tositumomab.

Incomplete restaging (CT scans, bone marrow [BM] biopsies, etc) was performed on 9 patients after completion of CHOP, rendering them inevaluable for response assessment. Two of these 9 patients had complete restaging after completion of antibody therapy, but 7 remained inevaluable for response after completion of the entire program.

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