Lipid peroxide levels in LDL before and after ebselen treatment
. | LOOH levels, nmol/mg apoB100 . | . | |
|---|---|---|---|
. | Before ebselen treatment . | After ebselen treatment . | |
| nLDL | ND | ND | |
| HbLDL | 31.3 ± 10.3 | ND | |
| CuLDL | 55 ± 16 | ND | |
| LDL- | 29.3 ± 6.5 | ND | |
. | LOOH levels, nmol/mg apoB100 . | . | |
|---|---|---|---|
. | Before ebselen treatment . | After ebselen treatment . | |
| nLDL | ND | ND | |
| HbLDL | 31.3 ± 10.3 | ND | |
| CuLDL | 55 ± 16 | ND | |
| LDL- | 29.3 ± 6.5 | ND | |
LDL was incubated with ebselen in the presence of glutathione for 1 hour at 37°C. Then ebselen was removed by gel filtration. LOOH levels were determined according to Muller et al.19 Data are mean ± SD.
ND indicates not detectable.