Table 3.

Microsatellite instability in CFUs from mice that received transplants of either wild-type or MSH2–/– bone marrow




Untreated primary recipient

TMZ-treated primary recipient*

TMZ-treated secondary recipient*

Untreated secondary recipient
Wild type   0 of 26   0 of 24   0 of 26   not done  
MSH2-/-
 
0 of 26
 
0 of 24
 
8 of 70
 
2 of 63
 



Untreated primary recipient

TMZ-treated primary recipient*

TMZ-treated secondary recipient*

Untreated secondary recipient
Wild type   0 of 26   0 of 24   0 of 26   not done  
MSH2-/-
 
0 of 26
 
0 of 24
 
8 of 70
 
2 of 63
 
*

Wild-type—treated versus MSH2-/-—treated recipients, P = .0152.

TMZ-treated secondary versus untreated secondary recipients, P = .09.

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