Table 2. Reactivity of patient sera... | American Society of Hematology

Table 2.

Reactivity of patient sera against components of the GPIb/IX complex

	CHOαβ			CHOβIX
Sera	Flow cytometry	MAIPA	Flow cytometry	MAIPA
AB	-	-	-	-
1	-	-	+	+
2	-	+	+	+
3	-	-	+	+
4	-	-	+	+
5	-	-	+	+
6	-	-	+	+
7	-	-	+	+

	CHOαβ			CHOβIX
Sera	Flow cytometry	MAIPA	Flow cytometry	MAIPA
AB	-	-	-	-
1	-	-	+	+
2	-	+	+	+
3	-	-	+	+
4	-	-	+	+
5	-	-	+	+
6	-	-	+	+
7	-	-	+	+

Sera from 7 patients was analyzed using CHOαβ and CHOβIX cells to assess binding to the individual components of the GPIb-IX complex. Both flow cytometry and the MAIPA assay were used. Negative controls were AB type sera, isotype-matched IgG, and patient sera in the absence of quinine. The results were expressed in positive (+) or negative (-).

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