Patient characteristics according to donor availability
. | No donor, N = 441 . | Donor, N = 293 . |
|---|---|---|
| Age, y, median (range) | 33 (15-45) | 35 (15-45) |
| Age group | ||
| Between 15 y and 25 y, n (%) | 114 (25.9) | 67 (22.9) |
| Between 26 y and 35 y, n (%) | 142 (32.2) | 88 (30.0) |
| Between 36 y and 45 y, n (%) | 185 (42.0) | 138 (47.1) |
| Median WBC count, × 109/L (range) | 19.2 (0.4-336) | 16.4 (0.6-420) |
| FAB type | ||
| Unknown, n (%) | 5 (1.1) | 2 (0.7) |
| M0, n (%) | 14 (3.2) | 9 (3.1) |
| M1, n (%) | 71 (16.1) | 46 (15.7) |
| M2, n (%) | 157 (35.6) | 106 (36.2) |
| M3, n (%)* | 2 (0.5) | 0 (0.0) |
| M4, n (%) | 75 (17.0) | 57 (19.5) |
| M4E, n (%) | 25 (5.6) | 22 (7.5) |
| M5, n (%) | 83 (18.8) | 40 (13.7) |
| M6-M7, n (%) | 9 (2.1) | 11 (3.7) |
| Courses needed to reach CR | ||
| 1, n (%) | 410 (93.0) | 267 (91.1) |
| 2, n (%) | 31 (7.0) | 26 (8.9) |
| Cytogenetics | ||
| Unknown, n (%) | 170 (38.5) | 118 (40.3) |
| Successful, n (%) | 271 (61.5) | 175 (59.7) |
| Good risk, n [%]† | 73 [26.9] | 50 [28.6] |
| Intermediate risk, n [%]‡ | 104 [38.4] | 61 [34.9] |
| Bad, n [%]§ | 56 [20.7] | 22 [12.6] |
| Very bad, n [%]∥ | 38 [14.0] | 42 [24.0] |
. | No donor, N = 441 . | Donor, N = 293 . |
|---|---|---|
| Age, y, median (range) | 33 (15-45) | 35 (15-45) |
| Age group | ||
| Between 15 y and 25 y, n (%) | 114 (25.9) | 67 (22.9) |
| Between 26 y and 35 y, n (%) | 142 (32.2) | 88 (30.0) |
| Between 36 y and 45 y, n (%) | 185 (42.0) | 138 (47.1) |
| Median WBC count, × 109/L (range) | 19.2 (0.4-336) | 16.4 (0.6-420) |
| FAB type | ||
| Unknown, n (%) | 5 (1.1) | 2 (0.7) |
| M0, n (%) | 14 (3.2) | 9 (3.1) |
| M1, n (%) | 71 (16.1) | 46 (15.7) |
| M2, n (%) | 157 (35.6) | 106 (36.2) |
| M3, n (%)* | 2 (0.5) | 0 (0.0) |
| M4, n (%) | 75 (17.0) | 57 (19.5) |
| M4E, n (%) | 25 (5.6) | 22 (7.5) |
| M5, n (%) | 83 (18.8) | 40 (13.7) |
| M6-M7, n (%) | 9 (2.1) | 11 (3.7) |
| Courses needed to reach CR | ||
| 1, n (%) | 410 (93.0) | 267 (91.1) |
| 2, n (%) | 31 (7.0) | 26 (8.9) |
| Cytogenetics | ||
| Unknown, n (%) | 170 (38.5) | 118 (40.3) |
| Successful, n (%) | 271 (61.5) | 175 (59.7) |
| Good risk, n [%]† | 73 [26.9] | 50 [28.6] |
| Intermediate risk, n [%]‡ | 104 [38.4] | 61 [34.9] |
| Bad, n [%]§ | 56 [20.7] | 22 [12.6] |
| Very bad, n [%]∥ | 38 [14.0] | 42 [24.0] |
Percentages between brackets were calculated for those with a successful examination.
M3 according to the cytology review, but M5 and M2 according to the local cytologist.
Presence of t(8;21) or inv(16).
NN or -Y only.
Presence of other abnormalities without good or very bad cytogenetic features.
Presence of -5, 5q-, -7, 7q-, complex abnormalities, abn 3q, t(9;22), t(6;9), or abn 11q23, and absence of good cytogenetic features.