Frequency of t(11;18) and BCL 10 nuclear expression in various MALT lymphomas
. | . | . | BCL10 nuclear expression . | . | . | ||
|---|---|---|---|---|---|---|---|
| Site of MALT lymphoma . | No. of cases . | t(11;18) (%) . | Moderate with API2-MALT1 fusion (%) . | Strong like in t(1;14) (%) . | Moderate but lacking API2-MALT1 fusion (%) . | ||
| Gastrointestinal tract | |||||||
| Stomach | 138 | 33 (23.9) | 30 of 30 (100) | 6 of 123 (4.9) | 26 of 87 (30) | ||
| Small intestine | 8 | 5 (62.5) | 1 of 1 (100) | 0 of 4 (0) | 0 of 3 (0) | ||
| IPSID | 22 | 0 (0) | — | 0 of 5 (0) | 1 of 5 (20) | ||
| Large intestine | 5 | 1 (20) | 1 of 1 (100) | 0 of 3 (0) | 0 of 2 (0) | ||
| Lung | 47 | 18 (38.3) | 17 of 17 (100) | 5 of 41 (12) | 5 of 19 (26) | ||
| Conjunctiva | 27 | 5 (18.5) | 3 of 3 (100) | 0 of 19 (0) | 8 of 16 (50) | ||
| Orbit | 28 | 4 (14.3) | 3 of 3 (100) | 0 of 19 (0) | 1 of 15 (6.7) | ||
| Salivary gland | 72 | 1 (1.4) | 1 of 1 (100) | 0 of 70 (0) | 15 of 69 (21.7) | ||
| Thyroid | 18 | 0 (0) | — | 0 of 14 (0) | 0 of 14 (0) | ||
| Skin | 27 | 0 (0) | — | 1 of 13 (7.7) | 0 of 12 (0) | ||
| Liver | 6 | 0 (0) | — | 0 of 4 (0) | 1 of 4 (25) | ||
| Other* | 19 | 0 (0) | — | 0 of 16 (0) | 3 of 16 (18.7) | ||
| Total | 417 | 67 (16.2) | 56 of 56 (100) | 12 of 331 (3.6) | 60 of 263 (23) | ||
. | . | . | BCL10 nuclear expression . | . | . | ||
|---|---|---|---|---|---|---|---|
| Site of MALT lymphoma . | No. of cases . | t(11;18) (%) . | Moderate with API2-MALT1 fusion (%) . | Strong like in t(1;14) (%) . | Moderate but lacking API2-MALT1 fusion (%) . | ||
| Gastrointestinal tract | |||||||
| Stomach | 138 | 33 (23.9) | 30 of 30 (100) | 6 of 123 (4.9) | 26 of 87 (30) | ||
| Small intestine | 8 | 5 (62.5) | 1 of 1 (100) | 0 of 4 (0) | 0 of 3 (0) | ||
| IPSID | 22 | 0 (0) | — | 0 of 5 (0) | 1 of 5 (20) | ||
| Large intestine | 5 | 1 (20) | 1 of 1 (100) | 0 of 3 (0) | 0 of 2 (0) | ||
| Lung | 47 | 18 (38.3) | 17 of 17 (100) | 5 of 41 (12) | 5 of 19 (26) | ||
| Conjunctiva | 27 | 5 (18.5) | 3 of 3 (100) | 0 of 19 (0) | 8 of 16 (50) | ||
| Orbit | 28 | 4 (14.3) | 3 of 3 (100) | 0 of 19 (0) | 1 of 15 (6.7) | ||
| Salivary gland | 72 | 1 (1.4) | 1 of 1 (100) | 0 of 70 (0) | 15 of 69 (21.7) | ||
| Thyroid | 18 | 0 (0) | — | 0 of 14 (0) | 0 of 14 (0) | ||
| Skin | 27 | 0 (0) | — | 1 of 13 (7.7) | 0 of 12 (0) | ||
| Liver | 6 | 0 (0) | — | 0 of 4 (0) | 1 of 4 (25) | ||
| Other* | 19 | 0 (0) | — | 0 of 16 (0) | 3 of 16 (18.7) | ||
| Total | 417 | 67 (16.2) | 56 of 56 (100) | 12 of 331 (3.6) | 60 of 263 (23) | ||
— indicates not applicable
Includes brain (4), bladder (4), tonsil (2), thymus (2), lacrimal (1), eye lid (2), breast (1), gall bladder (1), lip (1), and ovary (1)