Table 2.

Pharmacokinetics of 2-fluoroadenine




t1/2 terminal, h

AUC, μM/h

Cmax, μM

Clearance, L/h/m2

Trough blood level, μM
Mean   11.2   19.1   4.4   6.3   0.29  
Standard deviation   3.9   7.0   4.8   2.4   0.15  
Range
 
4.5-21.3
 
8.0-45.2
 
1.3-7.8
 
2.2-13.3
 
0.08-0.66
 



t1/2 terminal, h

AUC, μM/h

Cmax, μM

Clearance, L/h/m2

Trough blood level, μM
Mean   11.2   19.1   4.4   6.3   0.29  
Standard deviation   3.9   7.0   4.8   2.4   0.15  
Range
 
4.5-21.3
 
8.0-45.2
 
1.3-7.8
 
2.2-13.3
 
0.08-0.66
 

t1/2 indicates half-life time; and Cmax, maximum concentration

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