Table 5.

Multidrug resistance phenotype analysis at diagnosis



Without quinine

With quinine

Total

N
CR, %
N
CR, %
N
P
mdr1 gene+   36   80.0   40   87.5   76   NS  
mdr1 gene-   96   80.4   92   86.2   188   NS  
4 E3+   30   83.3   32   87.5   62   NS  
4 E3-   82   76.8   87   75.9   169   NS  
UIC2+   38   81.6   39   79.5   77   NS  
UIC2-   88   75.0   72   80.6   160   NS  
Rh123 efflux+   25   48.0   29   82.8   54   .01  
Rh 123 efflux-
 
53
 
86.8
 
53
 
77.4
 
106
 
NS
 


Without quinine

With quinine

Total

N
CR, %
N
CR, %
N
P
mdr1 gene+   36   80.0   40   87.5   76   NS  
mdr1 gene-   96   80.4   92   86.2   188   NS  
4 E3+   30   83.3   32   87.5   62   NS  
4 E3-   82   76.8   87   75.9   169   NS  
UIC2+   38   81.6   39   79.5   77   NS  
UIC2-   88   75.0   72   80.6   160   NS  
Rh123 efflux+   25   48.0   29   82.8   54   .01  
Rh 123 efflux-
 
53
 
86.8
 
53
 
77.4
 
106
 
NS
 

Criteria for positivity are indicated in “Patients and methods.” NS indicates not significant.

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