Abnormal cytogenetic results in MMM patients: comparison of WBC, CD34+ karyotypes
. | Conventional cytogenetics . | . | |
|---|---|---|---|
| Patient no. . | WBC . | CD34+ . | |
| 13 | 46, XY, t(4;12)(q32;q14)[16]/46, XY [2] | 46, XY, t(4;12)(q32;q14) [18] (100%) | |
| 17 | 47, XX, t(3;20)(q22;q13), der(4)t(4;10)(q26;q11), -10, +der(20)t(3;20)(q22;q13), + mar [13] | 47, XX, t(3;20)(q22;q13), t(4;10)(q26;q11), + mar [15] (100%) | |
| 19 | 46, XY, t(13;17)(q14;q25) [15] | 46, XY, t(13;17)(q14;q25) [17] (100%) | |
| 33 | 46, XY, del(13)(q11q13) [16]/46, XY [3] | 46, XY, del(13)(q11q13) [5]/46, XY [15] (33%) | |
| 57 | 46, XX, del(7)(q11) [8]/46, XX [2] | 46, XX [17] | |
. | Conventional cytogenetics . | . | |
|---|---|---|---|
| Patient no. . | WBC . | CD34+ . | |
| 13 | 46, XY, t(4;12)(q32;q14)[16]/46, XY [2] | 46, XY, t(4;12)(q32;q14) [18] (100%) | |
| 17 | 47, XX, t(3;20)(q22;q13), der(4)t(4;10)(q26;q11), -10, +der(20)t(3;20)(q22;q13), + mar [13] | 47, XX, t(3;20)(q22;q13), t(4;10)(q26;q11), + mar [15] (100%) | |
| 19 | 46, XY, t(13;17)(q14;q25) [15] | 46, XY, t(13;17)(q14;q25) [17] (100%) | |
| 33 | 46, XY, del(13)(q11q13) [16]/46, XY [3] | 46, XY, del(13)(q11q13) [5]/46, XY [15] (33%) | |
| 57 | 46, XX, del(7)(q11) [8]/46, XX [2] | 46, XX [17] | |
Chromosomes were classified according to the “International System for Human Cytogenetic Nomenclature” (ISCN, 1995).7 Respectively, 20 or 10 normal metaphases were required in minimum to consider WBC or CD34+ karyotypes as normal.