IκB protein expression and IKK and NF-κB activation in different HRS cell lines
. | Constitutive NF-κB . | IκBα . | IκBϵ . | Constitutive IKK . |
|---|---|---|---|---|
| HDLM-2 | +++ | wt | wt | ++ |
| L540 | +++ | wt | wt | ++ |
| L428 | +++ | mt | mt | ++ |
| KMH-2 | +++ | mt | wt | ++ |
| L1236 | +++ | wt | wt | ++ |
| HD-MyZ | + | wt | wt | (+) |
. | Constitutive NF-κB . | IκBα . | IκBϵ . | Constitutive IKK . |
|---|---|---|---|---|
| HDLM-2 | +++ | wt | wt | ++ |
| L540 | +++ | wt | wt | ++ |
| L428 | +++ | mt | mt | ++ |
| KMH-2 | +++ | mt | wt | ++ |
| L1236 | +++ | wt | wt | ++ |
| HD-MyZ | + | wt | wt | (+) |
The presence of wild-type (wt) or mutated (mt) IκB proteins as well as constitutive IKK or NF-κB activity is shown. (+) indicates very weak; +, weak; ++, strong; +++, very strong