EBV epitopes studied in ELIspot assays showing the proportion of a cohort of healthy EBV-seropositive individuals that made responses and the range of responders per million PBLs
HLA allele . | Epitope . | Antigen . | Proportion of tested individuals making response . | Range per 106 PBLs . | Reference for epitope . |
|---|---|---|---|---|---|
| A2 | GLCTLVAML | BMLF1 | 6/7 | 19-410 | 5 |
| A2 | CLGGLLTMV | LMP2 | 4/7 | 44-164 | 6 |
| A2 | LLWTLVVLL | LMP2 | 2/7 | 124-439 | 7 |
| A3 | RLRAEAGVK | EBNA3A | 1/1 | 125 | 8 |
| A11 | IVTDFSVIK | EBNA3B | 3/3 | 148-784 | 9 |
| A11 | AVFDRKSDAK | EBNA3B | 3/3 | 26-96 | 10 |
| A24 | RYSIFFDY | EBNA3A | 1/4 | 75 | 11 |
| A24 | TYGPVFMCL | LMP2 | 0/4 | — | 7 |
| B7 | RPPIFIRRL | EBNA3A | 2/4 | 100-432 | 12 |
| B7 | QPRAPIRPPI | EBNA3C | 3/4 | 80-384 | 12 |
| B8 | RAKFKQLL | BZLF1 | 4/4 | 88-1000 | 13 |
| B8 | FLRGRAYGL | EBNA3A | 4/4 | 23-380 | 14 |
| B8 | QAKWRLQTL | EBNA3A | 3/3 | 13-74 | 11 |
| B35 | HPVGEADYFEY | EBNA1 | 2/3 | 84-908 | 15 |
| B35 | YPLHEQHGM | EBNA3A | 2/2 | 81-267 | 11 |
| B44 | EGGVGWRHW | EBNA3C | 3/4 | 78-625 | 16 |
| B44 | EENLLDFVRF | EBNA3C | 2/3 | 43-210 | 17 |
| B60 | IEDPPFNSL | LMP2 | 2/2 | 127-277 | 7 |
HLA allele . | Epitope . | Antigen . | Proportion of tested individuals making response . | Range per 106 PBLs . | Reference for epitope . |
|---|---|---|---|---|---|
| A2 | GLCTLVAML | BMLF1 | 6/7 | 19-410 | 5 |
| A2 | CLGGLLTMV | LMP2 | 4/7 | 44-164 | 6 |
| A2 | LLWTLVVLL | LMP2 | 2/7 | 124-439 | 7 |
| A3 | RLRAEAGVK | EBNA3A | 1/1 | 125 | 8 |
| A11 | IVTDFSVIK | EBNA3B | 3/3 | 148-784 | 9 |
| A11 | AVFDRKSDAK | EBNA3B | 3/3 | 26-96 | 10 |
| A24 | RYSIFFDY | EBNA3A | 1/4 | 75 | 11 |
| A24 | TYGPVFMCL | LMP2 | 0/4 | — | 7 |
| B7 | RPPIFIRRL | EBNA3A | 2/4 | 100-432 | 12 |
| B7 | QPRAPIRPPI | EBNA3C | 3/4 | 80-384 | 12 |
| B8 | RAKFKQLL | BZLF1 | 4/4 | 88-1000 | 13 |
| B8 | FLRGRAYGL | EBNA3A | 4/4 | 23-380 | 14 |
| B8 | QAKWRLQTL | EBNA3A | 3/3 | 13-74 | 11 |
| B35 | HPVGEADYFEY | EBNA1 | 2/3 | 84-908 | 15 |
| B35 | YPLHEQHGM | EBNA3A | 2/2 | 81-267 | 11 |
| B44 | EGGVGWRHW | EBNA3C | 3/4 | 78-625 | 16 |
| B44 | EENLLDFVRF | EBNA3C | 2/3 | 43-210 | 17 |
| B60 | IEDPPFNSL | LMP2 | 2/2 | 127-277 | 7 |
LMP2 indicates latent membrane protein 2; EBNA3A, Epstein-Barr virus nuclear antigen 3A; and—, no response detected