Patient characteristics at entry into the study
Characteristic . | No. . |
---|---|
Number of patients; male:female | 236; 124:112 |
Age, y, male:female | |
0 to 4 | 152; 79:73 |
5 to 9 | 66; 40:26 |
Older than 9 | 18; 5:13 |
Median age, mo | 35 |
Hemoglobin level, g/L, mean±SD | 78±11 |
Hematocrit level, proportion of 1, mean±SD | .252±.037 |
Reticulocyte count, proportion of 1, mean±SD | .118±.065 |
Patients characterized for fetal hemoglobin | 131 |
Male, %, mean±SD, n = 74 | 10.1±5.8 |
Female, %, mean±SD, n = 57 | 11.9±5.8 |
Patients characterized for βs haplotype | 118 |
Homozygous Benin/Benin | 108 |
Heterozygous or atypical | 10 |
Patients characterized for α-globin gene status | 117 |
αα/αα | 62 |
αα/α- | 48 |
α-/α- | 7 |
Patients characterized for G6PD variant A | 107 |
Male (patients with A-) | 89 (17) |
Female (patients with A-) | 18 (8*) |
Characteristic . | No. . |
---|---|
Number of patients; male:female | 236; 124:112 |
Age, y, male:female | |
0 to 4 | 152; 79:73 |
5 to 9 | 66; 40:26 |
Older than 9 | 18; 5:13 |
Median age, mo | 35 |
Hemoglobin level, g/L, mean±SD | 78±11 |
Hematocrit level, proportion of 1, mean±SD | .252±.037 |
Reticulocyte count, proportion of 1, mean±SD | .118±.065 |
Patients characterized for fetal hemoglobin | 131 |
Male, %, mean±SD, n = 74 | 10.1±5.8 |
Female, %, mean±SD, n = 57 | 11.9±5.8 |
Patients characterized for βs haplotype | 118 |
Homozygous Benin/Benin | 108 |
Heterozygous or atypical | 10 |
Patients characterized for α-globin gene status | 117 |
αα/αα | 62 |
αα/α- | 48 |
α-/α- | 7 |
Patients characterized for G6PD variant A | 107 |
Male (patients with A-) | 89 (17) |
Female (patients with A-) | 18 (8*) |
One female patient was homozygous A-/A-