Table 1.

Definitions of SCD-related events


Painful crises: bone or abdominal pain or hand-foot syndrome lasting for more than 4 hours and attributable to SCD  
Stroke: isolated acute neurologic symptoms lasting for more than one day  
Acute splenic sequestration: sudden enlargement of spleen associated with a worsening of anemia requiring immediate blood transfusion  
Aplastic crisis: progressive worsening anemia with absence of reticulocytes  
Acute chest syndrome: chest/thoracic pain with infiltrate on chest x-ray and respiratory distress and significant drop in the hemoglobin level  
Malarial attack: > 2000 infected red blood cells/mm3
 

Painful crises: bone or abdominal pain or hand-foot syndrome lasting for more than 4 hours and attributable to SCD  
Stroke: isolated acute neurologic symptoms lasting for more than one day  
Acute splenic sequestration: sudden enlargement of spleen associated with a worsening of anemia requiring immediate blood transfusion  
Aplastic crisis: progressive worsening anemia with absence of reticulocytes  
Acute chest syndrome: chest/thoracic pain with infiltrate on chest x-ray and respiratory distress and significant drop in the hemoglobin level  
Malarial attack: > 2000 infected red blood cells/mm3
 
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