Table 1. Effect of growth factor... | American Society of Hematology

Table 1.

Effect of growth factor administration on human hematopoietic lineages in BM and spleen of NOD/SCID mice with transplanted CD34 cord blood cells

	Bone marrow					Spleen
Treatment (no. mice)	CD56⁺	CD19⁺	CD33⁺	CD56⁺	CD19⁺	CD33⁺
No treatment (20)	0.3 ± 0.1	87.0 ± 1.5	11.5 ± 1.5	0.3 ± 0.1	93.0 ± 1.2	3.0 ± 0.7
IL-15/FL (7)	3.9 ± 0.9^*	62.0 ± 4.0^*	27.0 ± 5.0^*	3.2 ± 1.4†	80.0 ± 5.0^*	6.6 ± 1.3†
IL-15/FL/SCF (6)	4.1 ± 1.1^*	64.0 ± 4.5^*	28.0 ± 3.0^*	4.4 ± 1.6^*	81.0 ± 4.0†	9.4 ± 2.5†
IL-15/FL/IL-12 (5)	4.9 ± 2.0^*	86.0 ± 4.0	6.3 ± 2.6	1.1 ± 0.2†	92.0 ± 1.0	2.6 ± 0.5
IL-15/FL/SCF/MGDF/IL-2 (3)	4.1 ± 1.3†	70.0 ± 3.5†	25.0 ± 3.5†	5.0 ± 1.4†	80.0 ± 1.5†	10.0 ± 2.0†

	Bone marrow					Spleen
Treatment (no. mice)	CD56⁺	CD19⁺	CD33⁺	CD56⁺	CD19⁺	CD33⁺
No treatment (20)	0.3 ± 0.1	87.0 ± 1.5	11.5 ± 1.5	0.3 ± 0.1	93.0 ± 1.2	3.0 ± 0.7
IL-15/FL (7)	3.9 ± 0.9^*	62.0 ± 4.0^*	27.0 ± 5.0^*	3.2 ± 1.4†	80.0 ± 5.0^*	6.6 ± 1.3†
IL-15/FL/SCF (6)	4.1 ± 1.1^*	64.0 ± 4.5^*	28.0 ± 3.0^*	4.4 ± 1.6^*	81.0 ± 4.0†	9.4 ± 2.5†
IL-15/FL/IL-12 (5)	4.9 ± 2.0^*	86.0 ± 4.0	6.3 ± 2.6	1.1 ± 0.2†	92.0 ± 1.0	2.6 ± 0.5
IL-15/FL/SCF/MGDF/IL-2 (3)	4.1 ± 1.3†	70.0 ± 3.5†	25.0 ± 3.5†	5.0 ± 1.4†	80.0 ± 1.5†	10.0 ± 2.0†

Values are mean percentages of human CD45⁺ cells ± SEMs.

P < .005.

P < .05.