Table 1.

Clinical parameters in 13 cases of DLBCL with late relapse





First episode


Second episode
Case
Sex
Age
Site of biopsy
Stage
Treatment
Interval, mo
Site of biopsy
Stage
Treatment
Outcome
1   M   66   Cervical LN   IIA   CHOP 6 ×   50   Inguinal LN   IIIA   IMVP, RT   CR  
2   M   65   Tonsil   IE   RT   53   Orbita   IE   Surgery   CR  
3   M   64   Testis   IE   CHVmP/VB 4 ×, RT   66   Brain   IE   RT   PR  
4   M   61   Larynx   IA   CHOP 6 ×   67   Axillary LN   IA   Ifos/VP16   CR  
5   F   78   Endometrium   IE   Hysterectomy   76   Submandibular LN   IIB   No Tx   PD  
6   M   61   Jejunum   IE   Surgery, RT   76   Jejunum   IVB   No Tx   DOOC  
7   F   76   Maxillary sinus   IIE   RT   81   Skin   IE   RT   CR  
8   F   78   Cervical LN   IA   RT   91   Axillary LN   IA   RT   CR  
9   M   46   Ileocoecal   IE/IVA   CHVmP/VB 6 ×   97   Tonsil   IVA   DHAP, Ifos/VP-16   SD  
10   M   59   Tonsil   IIE   ABMT   110   Cervical LN   IA   RT   CR  
11   M   64   Duodenum   IVA   CHOP 6 ×   141   Rectum   IV   No Tx   PR  
12   M   43   Cervical LN   IA   RT   144   Inguinal LN   IIIA   DHAP/PSCT, RT   PR  
13
 
M
 
62
 
Supraclavicular LN
 
IIIB
 
CHVmP/VB 8 ×
 
207
 
Stomach
 
IE
 
RT
 
PD
 




First episode


Second episode
Case
Sex
Age
Site of biopsy
Stage
Treatment
Interval, mo
Site of biopsy
Stage
Treatment
Outcome
1   M   66   Cervical LN   IIA   CHOP 6 ×   50   Inguinal LN   IIIA   IMVP, RT   CR  
2   M   65   Tonsil   IE   RT   53   Orbita   IE   Surgery   CR  
3   M   64   Testis   IE   CHVmP/VB 4 ×, RT   66   Brain   IE   RT   PR  
4   M   61   Larynx   IA   CHOP 6 ×   67   Axillary LN   IA   Ifos/VP16   CR  
5   F   78   Endometrium   IE   Hysterectomy   76   Submandibular LN   IIB   No Tx   PD  
6   M   61   Jejunum   IE   Surgery, RT   76   Jejunum   IVB   No Tx   DOOC  
7   F   76   Maxillary sinus   IIE   RT   81   Skin   IE   RT   CR  
8   F   78   Cervical LN   IA   RT   91   Axillary LN   IA   RT   CR  
9   M   46   Ileocoecal   IE/IVA   CHVmP/VB 6 ×   97   Tonsil   IVA   DHAP, Ifos/VP-16   SD  
10   M   59   Tonsil   IIE   ABMT   110   Cervical LN   IA   RT   CR  
11   M   64   Duodenum   IVA   CHOP 6 ×   141   Rectum   IV   No Tx   PR  
12   M   43   Cervical LN   IA   RT   144   Inguinal LN   IIIA   DHAP/PSCT, RT   PR  
13
 
M
 
62
 
Supraclavicular LN
 
IIIB
 
CHVmP/VB 8 ×
 
207
 
Stomach
 
IE
 
RT
 
PD
 

LN indicates lymph nodes; DLBCL, diffuse large B-cell lymphoma; CHOP, cyclofosfamide, adriamycin, vincristin, prednison; RT, radiotherapy; CHVmP/VB, cyclofosfamide, adriamycin, vimentin, prednisone, vinblastin, bleomycin; ABMT, autologous bone marrow transplantation; PSCT, peripheral stem cell transplantation; IMVP, ifosfamide, methotrexate, etoposide, prednisone; ifos/VP 16, ifosfamide, etoposide; No Tx, no treatment; DHAP, dexamethasone, adriamycin, cytarabin, cisplatin; and DOOC, died of other causes.

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