Clinical parameters in 13 cases of DLBCL with late relapse
. | . | . | First episode . | . | . | . | Second episode . | . | . | . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case . | Sex . | Age . | Site of biopsy . | Stage . | Treatment . | Interval, mo . | Site of biopsy . | Stage . | Treatment . | Outcome . | |||||
1 | M | 66 | Cervical LN | IIA | CHOP 6 × | 50 | Inguinal LN | IIIA | IMVP, RT | CR | |||||
2 | M | 65 | Tonsil | IE | RT | 53 | Orbita | IE | Surgery | CR | |||||
3 | M | 64 | Testis | IE | CHVmP/VB 4 ×, RT | 66 | Brain | IE | RT | PR | |||||
4 | M | 61 | Larynx | IA | CHOP 6 × | 67 | Axillary LN | IA | Ifos/VP16 | CR | |||||
5 | F | 78 | Endometrium | IE | Hysterectomy | 76 | Submandibular LN | IIB | No Tx | PD | |||||
6 | M | 61 | Jejunum | IE | Surgery, RT | 76 | Jejunum | IVB | No Tx | DOOC | |||||
7 | F | 76 | Maxillary sinus | IIE | RT | 81 | Skin | IE | RT | CR | |||||
8 | F | 78 | Cervical LN | IA | RT | 91 | Axillary LN | IA | RT | CR | |||||
9 | M | 46 | Ileocoecal | IE/IVA | CHVmP/VB 6 × | 97 | Tonsil | IVA | DHAP, Ifos/VP-16 | SD | |||||
10 | M | 59 | Tonsil | IIE | ABMT | 110 | Cervical LN | IA | RT | CR | |||||
11 | M | 64 | Duodenum | IVA | CHOP 6 × | 141 | Rectum | IV | No Tx | PR | |||||
12 | M | 43 | Cervical LN | IA | RT | 144 | Inguinal LN | IIIA | DHAP/PSCT, RT | PR | |||||
13 | M | 62 | Supraclavicular LN | IIIB | CHVmP/VB 8 × | 207 | Stomach | IE | RT | PD |
. | . | . | First episode . | . | . | . | Second episode . | . | . | . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case . | Sex . | Age . | Site of biopsy . | Stage . | Treatment . | Interval, mo . | Site of biopsy . | Stage . | Treatment . | Outcome . | |||||
1 | M | 66 | Cervical LN | IIA | CHOP 6 × | 50 | Inguinal LN | IIIA | IMVP, RT | CR | |||||
2 | M | 65 | Tonsil | IE | RT | 53 | Orbita | IE | Surgery | CR | |||||
3 | M | 64 | Testis | IE | CHVmP/VB 4 ×, RT | 66 | Brain | IE | RT | PR | |||||
4 | M | 61 | Larynx | IA | CHOP 6 × | 67 | Axillary LN | IA | Ifos/VP16 | CR | |||||
5 | F | 78 | Endometrium | IE | Hysterectomy | 76 | Submandibular LN | IIB | No Tx | PD | |||||
6 | M | 61 | Jejunum | IE | Surgery, RT | 76 | Jejunum | IVB | No Tx | DOOC | |||||
7 | F | 76 | Maxillary sinus | IIE | RT | 81 | Skin | IE | RT | CR | |||||
8 | F | 78 | Cervical LN | IA | RT | 91 | Axillary LN | IA | RT | CR | |||||
9 | M | 46 | Ileocoecal | IE/IVA | CHVmP/VB 6 × | 97 | Tonsil | IVA | DHAP, Ifos/VP-16 | SD | |||||
10 | M | 59 | Tonsil | IIE | ABMT | 110 | Cervical LN | IA | RT | CR | |||||
11 | M | 64 | Duodenum | IVA | CHOP 6 × | 141 | Rectum | IV | No Tx | PR | |||||
12 | M | 43 | Cervical LN | IA | RT | 144 | Inguinal LN | IIIA | DHAP/PSCT, RT | PR | |||||
13 | M | 62 | Supraclavicular LN | IIIB | CHVmP/VB 8 × | 207 | Stomach | IE | RT | PD |
LN indicates lymph nodes; DLBCL, diffuse large B-cell lymphoma; CHOP, cyclofosfamide, adriamycin, vincristin, prednison; RT, radiotherapy; CHVmP/VB, cyclofosfamide, adriamycin, vimentin, prednisone, vinblastin, bleomycin; ABMT, autologous bone marrow transplantation; PSCT, peripheral stem cell transplantation; IMVP, ifosfamide, methotrexate, etoposide, prednisone; ifos/VP 16, ifosfamide, etoposide; No Tx, no treatment; DHAP, dexamethasone, adriamycin, cytarabin, cisplatin; and DOOC, died of other causes.