Phospholipid fatty acid composition of infected erythrocyte ghosts and Plasmodium falciparum plasma membranes
. | IRBC . | P falciparum trophozoite . |
|---|---|---|
| Fatty acid | ||
| 14:0 | ND | 1.1±0.4 |
| 16:0 | 32.1±0.5* | 37.2±1.5† |
| 18:0 | 30.5±1.0* | 18.8±0.8† |
| 18:1, n-9 | 16.5±0.7‡ | 22.2±1.3† |
| 18:2, n-6 | 7.1±0.8* | 11.9±1.4‡ |
| 20:4, n-6 | 8.3±0.3* | 6.6±0.6‡ |
| 22:5, n-3 | ND | ND |
| 22:6, n-3 | 4.6±0.6§ | 2.2±0.5† |
| PUFA, % | 20.0 | 20.7 |
| DBI | 91.5 | 85.6 |
. | IRBC . | P falciparum trophozoite . |
|---|---|---|
| Fatty acid | ||
| 14:0 | ND | 1.1±0.4 |
| 16:0 | 32.1±0.5* | 37.2±1.5† |
| 18:0 | 30.5±1.0* | 18.8±0.8† |
| 18:1, n-9 | 16.5±0.7‡ | 22.2±1.3† |
| 18:2, n-6 | 7.1±0.8* | 11.9±1.4‡ |
| 20:4, n-6 | 8.3±0.3* | 6.6±0.6‡ |
| 22:5, n-3 | ND | ND |
| 22:6, n-3 | 4.6±0.6§ | 2.2±0.5† |
| PUFA, % | 20.0 | 20.7 |
| DBI | 91.5 | 85.6 |
PL fatty acid composition was determined and DBI calculated as described in Table 3. Results are the mean (±SD) of 3 determinations. ND indicates not detectable
Paired t test for comparison of IRBCs versus young NRBCs and young URBCs (Table 3), P < .01
Unpaired t test for comparison of trophozoites versus IRBC membranes, P < .01
Paired t test for comparison of IRBCs versus young NRBCs and young URBCs (Table 3), P < .05
Paired t test for comparison of IRBCs versus young NRBCs and young URBCs, P < .05 only versus young NRBCs (Table 3)