Phospholipid fatty acid composition of control and uninfected erythrocyte ghosts
. | NRBCs . | . | . | URBCs . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
. | Young . | Medium . | Old . | Young . | Medium . | Old . | ||||
| Fatty acid | ||||||||||
| 16:0 | 21.9±0.6 | 24.9±0.8* | 25.8±1.5* | 25.1±1.4† | 26.1±0.5 | 26.0±0.6 | ||||
| 18:0 | 19.4±2.2 | 19.1±1.2 | 18.2±1.0 | 18.6±0.1 | 18.6±0.5 | 18.6±0.8 | ||||
| 18:1, n-9 | 19.6±2.0 | 18.0±1.5 | 20.7±2.1 | 20.4±1 | 19.8±0.8 | 21.1±2.1 | ||||
| 18:2, n-6 | 11.6±0.1 | 12.7±0.3 | 12.5±0.2 | 11.1±0.1 | 12.0±0.3 | 11.8±1.4 | ||||
| 20:4, n-6 | 18.5±0.5 | 17.1±0.5* | 15.5±0.3‡ | 17.5±0.2§ | 15.5±0.2† | 15.8±0.2 | ||||
| 22:5, n-3 | 2.7±0.3 | 2.8±0.3 | 2.0±0.1 | 2.2±0.2 | 2.3±0.3 | 2.1±0.3 | ||||
| 22:6, n-3 | 5.9±0.3 | 5.4±0.5 | 4.8±0.2 | 4.8±0.8§ | 5.1±0.6 | 4.4±0.6 | ||||
| PUFA, % | 38.7 | 38.0 | 35.8 | 35.6 | 34.9 | 34.1 | ||||
| DBI | 165.7 | 158.2 | 146.5 | 152.4 | 147.9 | 144.8 | ||||
. | NRBCs . | . | . | URBCs . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
. | Young . | Medium . | Old . | Young . | Medium . | Old . | ||||
| Fatty acid | ||||||||||
| 16:0 | 21.9±0.6 | 24.9±0.8* | 25.8±1.5* | 25.1±1.4† | 26.1±0.5 | 26.0±0.6 | ||||
| 18:0 | 19.4±2.2 | 19.1±1.2 | 18.2±1.0 | 18.6±0.1 | 18.6±0.5 | 18.6±0.8 | ||||
| 18:1, n-9 | 19.6±2.0 | 18.0±1.5 | 20.7±2.1 | 20.4±1 | 19.8±0.8 | 21.1±2.1 | ||||
| 18:2, n-6 | 11.6±0.1 | 12.7±0.3 | 12.5±0.2 | 11.1±0.1 | 12.0±0.3 | 11.8±1.4 | ||||
| 20:4, n-6 | 18.5±0.5 | 17.1±0.5* | 15.5±0.3‡ | 17.5±0.2§ | 15.5±0.2† | 15.8±0.2 | ||||
| 22:5, n-3 | 2.7±0.3 | 2.8±0.3 | 2.0±0.1 | 2.2±0.2 | 2.3±0.3 | 2.1±0.3 | ||||
| 22:6, n-3 | 5.9±0.3 | 5.4±0.5 | 4.8±0.2 | 4.8±0.8§ | 5.1±0.6 | 4.4±0.6 | ||||
| PUFA, % | 38.7 | 38.0 | 35.8 | 35.6 | 34.9 | 34.1 | ||||
| DBI | 165.7 | 158.2 | 146.5 | 152.4 | 147.9 | 144.8 | ||||
PL fatty acid composition was determined by gas liquid chromatography. Results are the mean (±SD) of 4 to 8 determinations. DBI indicates double bond index (obtained by multiplying the percentage of each fatty acid by the number of double bonds in that acid)
Unpaired t test for comparison of medium and old NRBCs versus young NRBCs, P < .05
Paired t test for comparison of URBCs versus NRBCs of the same age, P < .01
Unpaired t test for comparison of medium and old NRBCs versus young NRBCs, P < .01
Paired t test for comparison of URBCs versus NRBCs of the same age, P < .05