Table 4.

Univariate (crude OR) and multivariate analysis (adjusted OR) of the features associated with the risk of developing hepatocellular carcinoma


Variables

Crude OR (95% CI)

Adjusted OR (95% CI)*
Age, older than 62 y   7.3 (1.4-38.2)   1.8 (0.1-36.9)  
Age at HCV infection, older than 40 y   6.9 (1.3-35.9)   3.4 (0.2-69.9)  
AFP level at entry, higher than 11 ng/mL   11.6 (2.6-51.5)   15.2 (2.7-85.7)  
ALT level at entry, higher than 176 IU/L   1.3 (0.1-10.7)   1.2 (0.1-11.8)  
Alcohol intake, more than 80 g/d
 
8.8 (2.0-38.5)
 
12.9 (2.4-68.7)
 

Variables

Crude OR (95% CI)

Adjusted OR (95% CI)*
Age, older than 62 y   7.3 (1.4-38.2)   1.8 (0.1-36.9)  
Age at HCV infection, older than 40 y   6.9 (1.3-35.9)   3.4 (0.2-69.9)  
AFP level at entry, higher than 11 ng/mL   11.6 (2.6-51.5)   15.2 (2.7-85.7)  
ALT level at entry, higher than 176 IU/L   1.3 (0.1-10.7)   1.2 (0.1-11.8)  
Alcohol intake, more than 80 g/d
 
8.8 (2.0-38.5)
 
12.9 (2.4-68.7)
 
*

For each variable, ORs are adjusted for the remaining 4 variables considered.

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