Patient and donor characteristics
. | ATG dose* . | . | |
|---|---|---|---|
| Characteristic . | High n = 46 . | Low n = 55 . | |
| Age, y | |||
| Recipient, median (range) | 49 (17-60) | 51 (23-61) | |
| Donor, median (range) | 46 (19-63) | 46 (22-77) | |
| Sex mismatch (%) | 26 (57) | 28 (51) | |
| Diagnosis (%) | |||
| Acute myeloblastic leukemia | 14 (30) | 8 (15) | |
| Myelodysplastic syndrome | 2 (4) | 1 (2) | |
| Acute lymphoblastic leukemia | 2 (4) | 2 (4) | |
| Chronic myeloid leukemia | 5 (11) | 3 (5) | |
| Chronic lymphocytic leukemia | 2 (4) | 3 (5) | |
| Hodgkin disease | 1 (2) | 1 (2) | |
| Non-Hodgkin lymphoma | 5 (11) | 10 (18) | |
| Multiple myeloma | 6 (13) | 5 (9) | |
| Nonhematologic malignancies | 9 (20) | 22 (40) | |
| Disease status (%) | |||
| Standard risk disease† | 14 (30) | 6 (11) | |
| Advanced disease | 32 (70) | 49 (89) | |
| Cytomegalovirus status (%) | |||
| Seronegative, with seronegative donor | 4 (9) | 13 (24) | |
| ABO mismatch (%) | 15 (33) | 13 (24) | |
| Graft source (%) | |||
| Bone marrow | 42 (91) | 5 (9) | |
| Peripheral blood stem cells | 4 (9) | 50 (91) | |
. | ATG dose* . | . | |
|---|---|---|---|
| Characteristic . | High n = 46 . | Low n = 55 . | |
| Age, y | |||
| Recipient, median (range) | 49 (17-60) | 51 (23-61) | |
| Donor, median (range) | 46 (19-63) | 46 (22-77) | |
| Sex mismatch (%) | 26 (57) | 28 (51) | |
| Diagnosis (%) | |||
| Acute myeloblastic leukemia | 14 (30) | 8 (15) | |
| Myelodysplastic syndrome | 2 (4) | 1 (2) | |
| Acute lymphoblastic leukemia | 2 (4) | 2 (4) | |
| Chronic myeloid leukemia | 5 (11) | 3 (5) | |
| Chronic lymphocytic leukemia | 2 (4) | 3 (5) | |
| Hodgkin disease | 1 (2) | 1 (2) | |
| Non-Hodgkin lymphoma | 5 (11) | 10 (18) | |
| Multiple myeloma | 6 (13) | 5 (9) | |
| Nonhematologic malignancies | 9 (20) | 22 (40) | |
| Disease status (%) | |||
| Standard risk disease† | 14 (30) | 6 (11) | |
| Advanced disease | 32 (70) | 49 (89) | |
| Cytomegalovirus status (%) | |||
| Seronegative, with seronegative donor | 4 (9) | 13 (24) | |
| ABO mismatch (%) | 15 (33) | 13 (24) | |
| Graft source (%) | |||
| Bone marrow | 42 (91) | 5 (9) | |
| Peripheral blood stem cells | 4 (9) | 50 (91) | |