Summary of frequently reported (greater than 10%) nonhemopoietic treatment-related adverse events by maximum NCI grade for all patients on thalidomide alone, n = 75
. | Total . | . | Grade 1 . | . | Grade 2 . | . | Grade 3* . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Adverse event . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | ||||
| Nausea | 12 | 16 | 6 | 8 | 6 | 8 | 0 | 0 | ||||
| Constipation | 56 | 75 | 13 | 17 | 33 | 44 | 10 | 13 | ||||
| Rash/desquamation | 13 | 17 | 5 | 7 | 6 | 8 | 2 | 3 | ||||
| Headache | 9 | 12 | 4 | 5 | 5 | 7 | 0 | 0 | ||||
| Fatigue | 56 | 75 | 21 | 28 | 29 | 39 | 6 | 8 | ||||
| Depressed level of consciousness | 16 | 21 | 9 | 12 | 5 | 7 | 2 | 3 | ||||
| Motor neuropathy | 22 | 29 | 13 | 17 | 6 | 8 | 3 | 4 | ||||
| Sensory neuropathy | 35 | 47 | 12 | 16 | 16 | 21 | 7 | 9 | ||||
| Dizziness | 9 | 12 | 5 | 7 | 4 | 5 | 0 | 0 | ||||
| Mouth dryness | 10 | 13 | 6 | 8 | 4 | 5 | 0 | 0 | ||||
. | Total . | . | Grade 1 . | . | Grade 2 . | . | Grade 3* . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Adverse event . | No. . | % . | No. . | % . | No. . | % . | No. . | % . | ||||
| Nausea | 12 | 16 | 6 | 8 | 6 | 8 | 0 | 0 | ||||
| Constipation | 56 | 75 | 13 | 17 | 33 | 44 | 10 | 13 | ||||
| Rash/desquamation | 13 | 17 | 5 | 7 | 6 | 8 | 2 | 3 | ||||
| Headache | 9 | 12 | 4 | 5 | 5 | 7 | 0 | 0 | ||||
| Fatigue | 56 | 75 | 21 | 28 | 29 | 39 | 6 | 8 | ||||
| Depressed level of consciousness | 16 | 21 | 9 | 12 | 5 | 7 | 2 | 3 | ||||
| Motor neuropathy | 22 | 29 | 13 | 17 | 6 | 8 | 3 | 4 | ||||
| Sensory neuropathy | 35 | 47 | 12 | 16 | 16 | 21 | 7 | 9 | ||||
| Dizziness | 9 | 12 | 5 | 7 | 4 | 5 | 0 | 0 | ||||
| Mouth dryness | 10 | 13 | 6 | 8 | 4 | 5 | 0 | 0 | ||||
There were no Grade 4 adverse events.