Main toxicities by course
. | Cyclophosphamide . | Cytarabine . | Melphalan . | Mitoxantrone and melphalan . | Overall . |
|---|---|---|---|---|---|
| Grade 5 | |||||
| Cardiac | — | — | — | 4 | 4 |
| Grade 4 | |||||
| Hematologic | 100 | 100 | 100 | 100 | 100 |
| Mucositis | — | — | 4 | 8 | 11 |
| Grade 3 | |||||
| FUO/doc infection | 11 | 14 | 21 | 21 | 64 |
| Hepatic | — | 4 | — | — | — |
| Neurologic | — | 8 | — | — | — |
| CMV reactivation | — | — | 7 | 17 | 21 |
. | Cyclophosphamide . | Cytarabine . | Melphalan . | Mitoxantrone and melphalan . | Overall . |
|---|---|---|---|---|---|
| Grade 5 | |||||
| Cardiac | — | — | — | 4 | 4 |
| Grade 4 | |||||
| Hematologic | 100 | 100 | 100 | 100 | 100 |
| Mucositis | — | — | 4 | 8 | 11 |
| Grade 3 | |||||
| FUO/doc infection | 11 | 14 | 21 | 21 | 64 |
| Hepatic | — | 4 | — | — | — |
| Neurologic | — | 8 | — | — | — |
| CMV reactivation | — | — | 7 | 17 | 21 |
— indicates not applicable; FUO, fever of unknown origin; and doc, documented infection