Table 2.

Characteristics of control subjects according to current estrogen use, factor XIIIA Val34Leu genotype, and factor XIIIB His95Arg genotype

Estrogen use
Factor XIIIA genotype
Factor XIIIB genotype
Current (N = 268)
Not current (N = 453)
Leu34+ (N = 315)
Leu34− (N = 406)
Arg95+ (N = 144)
Arg95− (N = 577)
Characteristic
Mean or %
Mean or %
Mean or %
Age (y)   64.9   68.9   67.6   67.3   66.2   67.8  
Black (%)   1.1   2.6   1.6   2.5   9.7   0.2† 
Current smoker (%)   10.1   9.9   9.2   10.6   12.5   9.4  
Diabetes (%)   3.4   8.8†  6.4   7.1   9.0   6.2  
Any CVD* (%)   10.8   14.6   12.4   13.8   11.8   13.5  
Body mass index (kg/m2)   28.5   28.4   28.6   28.3   29.2   28.2  
Systolic blood pressure (mm Hg)   135.4   139.9†  138.8   137.8   138.1   138.3  
Cholesterol level (mg/dL)   227.9   234.0   230.7   232.5   231.4   231.8  
Current estrogen use (%)
 		 100.0
 		 0.0
 		 39.1
 		 35.7
 		 36.8
 		 37.3
 
Estrogen use
Factor XIIIA genotype
Factor XIIIB genotype
Current (N = 268)
Not current (N = 453)
Leu34+ (N = 315)
Leu34− (N = 406)
Arg95+ (N = 144)
Arg95− (N = 577)
Characteristic
Mean or %
Mean or %
Mean or %
Age (y)   64.9   68.9   67.6   67.3   66.2   67.8  
Black (%)   1.1   2.6   1.6   2.5   9.7   0.2† 
Current smoker (%)   10.1   9.9   9.2   10.6   12.5   9.4  
Diabetes (%)   3.4   8.8†  6.4   7.1   9.0   6.2  
Any CVD* (%)   10.8   14.6   12.4   13.8   11.8   13.5  
Body mass index (kg/m2)   28.5   28.4   28.6   28.3   29.2   28.2  
Systolic blood pressure (mm Hg)   135.4   139.9†  138.8   137.8   138.1   138.3  
Cholesterol level (mg/dL)   227.9   234.0   230.7   232.5   231.4   231.8  
Current estrogen use (%)
 		 100.0
 		 0.0
 		 39.1
 		 35.7
 		 36.8
 		 37.3
 
*

CVD indicates cardiovascular disease.

†

P < .05 for the comparison between exposed and unexposed.

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