Table 1.

Characteristics of female MI cases and controls



Cases (N = 234)

Controls (N = 721)
Characteristic
Mean or %
Age (years)   67.3   67.5  
Black (%)   2.6   2.1  
Time enrolled in Group Health Cooperative (years)   19.2   22.5  
Current estrogen use (%)   34.2   37.2  
Estrogen alone   18.8   20.9  
Estrogen plus progestin   15.4   16.2  
Hysterectomy (%)   40.2   40.6  
Treated hypertension (%)   46.2   53.4  
Current smoker (%)   27.4   10.0 
Diabetes (%)   23.5   6.8 
History of angina (%)   17.1   6.8 
Any cardiovascular disease* (%)   28.6   13.2 
Any family history of MI (%)   58.3   46.5 
Body mass index (kg/m2)   29.2   28.4  
Systolic blood pressure (mm Hg)   143.7   138.2 
Diastolic blood pressure (mm Hg)   80.1   79.7  
Cholesterol level (mg/dL)   246.3   231.7 
Glucose level (mg/dL)   126.8   106.4 
Factor XIIIA Val34Leu genotype (%)    
Val/Val   65.0   56.3  
Val/Leu   29.1   36.1  
Leu/Leu   6.0   7.6  
Factor XIIIB His95Arg genotype (%)    
His/His   82.5   80.0  
His/Arg   16.7   17.3  
Arg/Arg
 
0.9
 
2.6
 


Cases (N = 234)

Controls (N = 721)
Characteristic
Mean or %
Age (years)   67.3   67.5  
Black (%)   2.6   2.1  
Time enrolled in Group Health Cooperative (years)   19.2   22.5  
Current estrogen use (%)   34.2   37.2  
Estrogen alone   18.8   20.9  
Estrogen plus progestin   15.4   16.2  
Hysterectomy (%)   40.2   40.6  
Treated hypertension (%)   46.2   53.4  
Current smoker (%)   27.4   10.0 
Diabetes (%)   23.5   6.8 
History of angina (%)   17.1   6.8 
Any cardiovascular disease* (%)   28.6   13.2 
Any family history of MI (%)   58.3   46.5 
Body mass index (kg/m2)   29.2   28.4  
Systolic blood pressure (mm Hg)   143.7   138.2 
Diastolic blood pressure (mm Hg)   80.1   79.7  
Cholesterol level (mg/dL)   246.3   231.7 
Glucose level (mg/dL)   126.8   106.4 
Factor XIIIA Val34Leu genotype (%)    
Val/Val   65.0   56.3  
Val/Leu   29.1   36.1  
Leu/Leu   6.0   7.6  
Factor XIIIB His95Arg genotype (%)    
His/His   82.5   80.0  
His/Arg   16.7   17.3  
Arg/Arg
 
0.9
 
2.6
 
*

Defined as history of angina, congestive heart failure, stroke, transient ischemic attack, claudication, or surgical treatment for any of these conditions.

P < .05 for the comparison between cases and controls.

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