Relation of ADAMTS13 activity to clinical categories of 142 patients with clinically diagnosed TTP-HUS
. | ADAMTS13 activity categories, no. of patients (%) . | . | . | . | |||
|---|---|---|---|---|---|---|---|
| Clinical categories, (no. of patients) . | Less than 5% . | 5%-9% . | 10%-25% . | More than 25% . | |||
| Stem cell transplantation (7) | 0 | 0 | 1 (14) | 6 (86) | |||
| Pregnant/postpartum (10) | 2 (20) | 0 | 0 | 8 (80) | |||
| Drug associated (21) | 0 | 0 | 1 (5) | 20 (95) | |||
| Bloody diarrhea (10) | 0 | 1 (10) | 0 | 9 (90) | |||
| Additional/alternative disorders (46) | 0 | 2 (4) | 10 (22) | 34 (74) | |||
| Idiopathic (48) | 16 (33) | 4 (8) | 11 (23) | 17 (36) | |||
| Total patients (142) | 18 (13) | 7 (5) | 23 (16) | 94 (66) | |||
. | ADAMTS13 activity categories, no. of patients (%) . | . | . | . | |||
|---|---|---|---|---|---|---|---|
| Clinical categories, (no. of patients) . | Less than 5% . | 5%-9% . | 10%-25% . | More than 25% . | |||
| Stem cell transplantation (7) | 0 | 0 | 1 (14) | 6 (86) | |||
| Pregnant/postpartum (10) | 2 (20) | 0 | 0 | 8 (80) | |||
| Drug associated (21) | 0 | 0 | 1 (5) | 20 (95) | |||
| Bloody diarrhea (10) | 0 | 1 (10) | 0 | 9 (90) | |||
| Additional/alternative disorders (46) | 0 | 2 (4) | 10 (22) | 34 (74) | |||
| Idiopathic (48) | 16 (33) | 4 (8) | 11 (23) | 17 (36) | |||
| Total patients (142) | 18 (13) | 7 (5) | 23 (16) | 94 (66) | |||
ADAMTS13 activity was measured on serum samples collected immediately before the first plasma exchange treatment on 142 (88%) of 161 consecutive patients with clinically diagnosed TTP-HUS. Clinical categories are defined in “Patients and methods.”