Table 5.

Operating characteristics of clofarabine versus clofarabine + ara-C versus clofarabine + idarubicin trial: selection probabilities



Selection probabilities
Clinical scenario
Arm 1
Arm 2
Arm 3
No arm
Arm 3 has 26% CR rate, 20% death rate; arms 1 and 2 have the same rates as with IA   0.06   0.06   0.78   0.10  
All arms the same as IA
 
0.18
 
0.18
 
0.18
 
0.46
 


Selection probabilities
Clinical scenario
Arm 1
Arm 2
Arm 3
No arm
Arm 3 has 26% CR rate, 20% death rate; arms 1 and 2 have the same rates as with IA   0.06   0.06   0.78   0.10  
All arms the same as IA
 
0.18
 
0.18
 
0.18
 
0.46
 
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