Operating characteristics of double-induction trial
. | . | Achieved sample size percentiles . | . | . | ||
---|---|---|---|---|---|---|
Clinical scenario . | Probability of early termination . | 25th . | 50th . | 75th . | ||
Same as historical rates | 0.69 | 15 | 25 | 50 | ||
82% success rate and 18% death rate | 0.21 | 50 | 50 | 50 | ||
67% success rate and 33% death rate | 0.96 | 10 | 15 | 20 | ||
50% ineligibility rate | 0.89 | 10 | 15 | 30 |
. | . | Achieved sample size percentiles . | . | . | ||
---|---|---|---|---|---|---|
Clinical scenario . | Probability of early termination . | 25th . | 50th . | 75th . | ||
Same as historical rates | 0.69 | 15 | 25 | 50 | ||
82% success rate and 18% death rate | 0.21 | 50 | 50 | 50 | ||
67% success rate and 33% death rate | 0.96 | 10 | 15 | 20 | ||
50% ineligibility rate | 0.89 | 10 | 15 | 30 |