Age at primary diagnosis and clonal cytogenetic abnormalities in t-MDS/t-AML
Age range in quartiles, y . | No. patients . | Abnormality 5 (%) . | Abnormality 7 (%) . | Abnormalities 5 and 7 (%) . | Balanced rearrangement* (%) . | Other abnormalities (%) . | Normal (%) . |
|---|---|---|---|---|---|---|---|
| 3-36 | 73 | 11 (15) | 21 (29) | 14 (19) | 7 (10) | 12 (16) | 8 (11) |
| 37-50 | 76 | 17 (22) | 28 (37) | 16 (21) | 9 (12) | 4 (5) | 2 (3) |
| 51-61 | 70 | 15 (21) | 19 (27) | 14 (20) | 8 (11) | 10 (14) | 4 (6) |
| 62-83 | 80 | 18 (23) | 16 (20) | 19 (24) | 7 (9) | 10 (13) | 10 (13) |
| Totals | 299 | 61 (20) | 84 (28) | 63 (21) | 31 (10) | 36 (12) | 24 (8) |
Age range in quartiles, y . | No. patients . | Abnormality 5 (%) . | Abnormality 7 (%) . | Abnormalities 5 and 7 (%) . | Balanced rearrangement* (%) . | Other abnormalities (%) . | Normal (%) . |
|---|---|---|---|---|---|---|---|
| 3-36 | 73 | 11 (15) | 21 (29) | 14 (19) | 7 (10) | 12 (16) | 8 (11) |
| 37-50 | 76 | 17 (22) | 28 (37) | 16 (21) | 9 (12) | 4 (5) | 2 (3) |
| 51-61 | 70 | 15 (21) | 19 (27) | 14 (20) | 8 (11) | 10 (14) | 4 (6) |
| 62-83 | 80 | 18 (23) | 16 (20) | 19 (24) | 7 (9) | 10 (13) | 10 (13) |
| Totals | 299 | 61 (20) | 84 (28) | 63 (21) | 31 (10) | 36 (12) | 24 (8) |
P = .34.
Two patients, one each with abnormal chromosome 5 or 7, are counted only in the balanced rearrangement category because of t(3;21) or inv(16).