Table 1.

Primary diagnoses and primary cytotoxic therapy received by 306 patients in whom t-MDS/t-AML developed


Primary diagnosis

No. patients

CT only (%)

RT only (%)

CMT (%)
No malignancy   18   12 (67)   2 (11)   4 (22)  
Hematologic malignancy   171   69 (40)   5 (3)   97 (57)  
Hodgkin disease   77   18 (23)   4 (5)   55 (71)  
Non-Hodgkin lymphoma   70   33 (47)   1 (1)   36 (51)  
Myeloma   23   17 (74)   0   6 (26)  
Other*  1   1 (100)   0   0  
Solid tumor   117  40 (35)   36 (32)   38 (33)  
Breast   32  11 (35)   5 (16)   15 (48)  
Ovary   15   12 (80)   1 (7)   2 (13)  
Prostate   13§  0   11 (100)   0  
Lung   9   5 (56)   2 (22)   2 (22)  
Cervix   7   0   4 (57)   3 (43)  
Other*  41   12 (29)   13 (32)   16 (39)  
Totals
 
306
 
121 (40)
 
43 (14)
 
139 (46)
 

Primary diagnosis

No. patients

CT only (%)

RT only (%)

CMT (%)
No malignancy   18   12 (67)   2 (11)   4 (22)  
Hematologic malignancy   171   69 (40)   5 (3)   97 (57)  
Hodgkin disease   77   18 (23)   4 (5)   55 (71)  
Non-Hodgkin lymphoma   70   33 (47)   1 (1)   36 (51)  
Myeloma   23   17 (74)   0   6 (26)  
Other*  1   1 (100)   0   0  
Solid tumor   117  40 (35)   36 (32)   38 (33)  
Breast   32  11 (35)   5 (16)   15 (48)  
Ovary   15   12 (80)   1 (7)   2 (13)  
Prostate   13§  0   11 (100)   0  
Lung   9   5 (56)   2 (22)   2 (22)  
Cervix   7   0   4 (57)   3 (43)  
Other*  41   12 (29)   13 (32)   16 (39)  
Totals
 
306
 
121 (40)
 
43 (14)
 
139 (46)
 
*

Smaller diagnostic groups were not further subdivided by primary diagnosis.

In 3 patients, the primary therapy was incompletely known.

In 1 patient, the primary therapy was incompletely known.

§

In 2 patients, the primary therapy was incompletely known.

or Create an Account

Close Modal
Close Modal