Table 2. NB1 cDNA polymorphisms . . .... | American Society of Hematology

Table 2.

NB1 cDNA polymorphisms

			Polymorphisms
			34	119	141	778	1069	1318
	%		C>G	A>T	G>A	A>C	G>A	G>A
Donor	NB1⁺	mRNA	Pro→Ala	His→Leu	Leu	Ile→Leu	Ala→Thr	Gly→Arg
1	83	2212	c/G	a/T	g/A	a/C	g	g
2	81	743	G	a	g	a	g	A
3	81	941	c	a	g	a/C	g/A	g
4	76	1799	G	a	A	a	g	A
5	75	6254	c/G	a	g	a	g	g
6	74	397	G	a	A	a	g	A
7	71	883	G	T	A	a	g	A
8	68	7357	c/G	a	g/A	a/C	g	g
9	63	3074	c	a	g	a	g	g
10	61	6456	c/G	a	g	a	g	g
11	61	3246	c	a	g	a	g	g
12	37	33	G	a	g	a/C	g/A	g
13	36	305	G	a	g	C	A	g
14	32	1386	G	T	A	C	A	g
15	26	272	G	a	g	C	A	g
16	22	66	G	a	g/A	C	g/A	g
17	20	204	G	T	A	C	A	g
18	13	66	G	a	g	C	g/A	g
19	10	463	G	a	g	C	A	g
P		.001	.02	.778	.840	<.001	<.001	.206

			Polymorphisms
			34	119	141	778	1069	1318
	%		C>G	A>T	G>A	A>C	G>A	G>A
Donor	NB1⁺	mRNA	Pro→Ala	His→Leu	Leu	Ile→Leu	Ala→Thr	Gly→Arg
1	83	2212	c/G	a/T	g/A	a/C	g	g
2	81	743	G	a	g	a	g	A
3	81	941	c	a	g	a/C	g/A	g
4	76	1799	G	a	A	a	g	A
5	75	6254	c/G	a	g	a	g	g
6	74	397	G	a	A	a	g	A
7	71	883	G	T	A	a	g	A
8	68	7357	c/G	a	g/A	a/C	g	g
9	63	3074	c	a	g	a	g	g
10	61	6456	c/G	a	g	a	g	g
11	61	3246	c	a	g	a	g	g
12	37	33	G	a	g	a/C	g/A	g
13	36	305	G	a	g	C	A	g
14	32	1386	G	T	A	C	A	g
15	26	272	G	a	g	C	A	g
16	22	66	G	a	g/A	C	g/A	g
17	20	204	G	T	A	C	A	g
18	13	66	G	a	g	C	g/A	g
19	10	463	G	a	g	C	A	g
P		.001	.02	.778	.840	<.001	<.001	.206

NB1 cDNA polymorphisms and their appearance in donors with a large (> 60%, donors 1-11) and a small (< 40%, donors 12-19) NB1 GP⁺ subpopulation; mRNA: copies/5 × 10⁶ cells; 2 letters: heterozygous expression; numbering according to Kissel et al.⁶ A significant association can be found between a low percentage of NB1 GP⁺ neutrophils and the polymorphisms 34C>G, 778A>C, and 1069G>A. The individuals with a small NB1 GP-bearing neutrophil subpopulation show also a significant lower NB1 GP mRNA formation

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