Multivariate Cox regression models
Factor . | Hazard ratio . | P* . | [95% Confidence interval] . |
|---|---|---|---|
| Outcome/survival Flow score | |||
| Mild | 1.0 | — | — |
| Moderate | 3.8 | < .01 | [1.6,9.3] |
| Severe | 2.4 | .07 | [0.9,6.3] |
| Overall likelihood ratio, P | < .01 | ||
| Morph blast, % | |||
| Less than 5 | 1.0 | — | — |
| 5-10 | 1.8 | .18 | [0.8,4.2] |
| 11-20 | 1.3 | .55 | [0.5,3.6] |
| 21 or more | 1.9 | .29 | [0.6,6.2] |
| Overall likelihood ratio, P | .54 | ||
| Karyotype group | |||
| Good | 1.0 | — | — |
| Intermediate | 0.8 | .68 | [0.3,2.1] |
| Poor | 2.9 | <.01 | [1.5,5.3] |
| Overall likelihood ratio, P | <.01 | ||
| Cytopenias | |||
| 0/1 | 1.0 | — | — |
| 2/3 | 1.2 | .63 | [0.6,2.3] |
| Outcome/relapse Flow score | |||
| Mild | 1.0 | — | — |
| Moderate | 6.6 | .06 | [0.7,62.0] |
| Severe | 11.8 | < .01 | [1.3,104.3] |
| Overall likelihood ratio, P | .02 | ||
| Morph blast, % Less than 5 | 1.0 | — | — |
| 5-10 | 1.1 | .94 | [0.3,4.4] |
| 11-20 | 1.5 | .56 | [0.4,6.7] |
| 21 or more | 2.6 | .27 | [0.5,12.9] |
| Overall likelihood ratio, P | .68 | ||
| Karyotype group | |||
| Good | 1.0 | — | — |
| Intermediate | 1.3 | .77 | [0.2,7.0] |
| Poor | 9.0 | < .01 | [2.8,28.8] |
| Overall likelihood ratio, P | < .01 | ||
| Cytopenias | |||
| 0/1 | 1.0 | — | — |
| 2/3 | 1.2 | .75 | [0.4,3.9] |
| Outcome/nonrelapse mortality Flow score | |||
| Mild | 1.0 | — | — |
| Moderate | 3.1 | .01 | [1.2,7.7] |
| Severe | 1.1 | .81 | [0.4,3.4] |
| Overall likelihood ratio, P | .03 | ||
| Morph blast, % Less than 5 | — | — | — |
| 5-10 | 2.2 | .13 | [0.8,5.8] |
| 11-20 | 1.6 | .45 | [0.5,5.1] |
| 21 or more | 1.5 | .63 | [0.3,8.3] |
| Overall likelihood ratio, P | .51 | ||
| Karyotype group | |||
| Good | — | — | — |
| Intermediate | 0.6 | .40 | [0.2,1.9] |
| Poor | 1.9 | .09 | [0.9,4.0] |
| Overall likelihood ratio, P | .09 | ||
| Cytopenias | |||
| 0/1 | — | — | — |
| 2/3 | 1.4 | .36 | [0.6,3.1] |
Factor . | Hazard ratio . | P* . | [95% Confidence interval] . |
|---|---|---|---|
| Outcome/survival Flow score | |||
| Mild | 1.0 | — | — |
| Moderate | 3.8 | < .01 | [1.6,9.3] |
| Severe | 2.4 | .07 | [0.9,6.3] |
| Overall likelihood ratio, P | < .01 | ||
| Morph blast, % | |||
| Less than 5 | 1.0 | — | — |
| 5-10 | 1.8 | .18 | [0.8,4.2] |
| 11-20 | 1.3 | .55 | [0.5,3.6] |
| 21 or more | 1.9 | .29 | [0.6,6.2] |
| Overall likelihood ratio, P | .54 | ||
| Karyotype group | |||
| Good | 1.0 | — | — |
| Intermediate | 0.8 | .68 | [0.3,2.1] |
| Poor | 2.9 | <.01 | [1.5,5.3] |
| Overall likelihood ratio, P | <.01 | ||
| Cytopenias | |||
| 0/1 | 1.0 | — | — |
| 2/3 | 1.2 | .63 | [0.6,2.3] |
| Outcome/relapse Flow score | |||
| Mild | 1.0 | — | — |
| Moderate | 6.6 | .06 | [0.7,62.0] |
| Severe | 11.8 | < .01 | [1.3,104.3] |
| Overall likelihood ratio, P | .02 | ||
| Morph blast, % Less than 5 | 1.0 | — | — |
| 5-10 | 1.1 | .94 | [0.3,4.4] |
| 11-20 | 1.5 | .56 | [0.4,6.7] |
| 21 or more | 2.6 | .27 | [0.5,12.9] |
| Overall likelihood ratio, P | .68 | ||
| Karyotype group | |||
| Good | 1.0 | — | — |
| Intermediate | 1.3 | .77 | [0.2,7.0] |
| Poor | 9.0 | < .01 | [2.8,28.8] |
| Overall likelihood ratio, P | < .01 | ||
| Cytopenias | |||
| 0/1 | 1.0 | — | — |
| 2/3 | 1.2 | .75 | [0.4,3.9] |
| Outcome/nonrelapse mortality Flow score | |||
| Mild | 1.0 | — | — |
| Moderate | 3.1 | .01 | [1.2,7.7] |
| Severe | 1.1 | .81 | [0.4,3.4] |
| Overall likelihood ratio, P | .03 | ||
| Morph blast, % Less than 5 | — | — | — |
| 5-10 | 2.2 | .13 | [0.8,5.8] |
| 11-20 | 1.6 | .45 | [0.5,5.1] |
| 21 or more | 1.5 | .63 | [0.3,8.3] |
| Overall likelihood ratio, P | .51 | ||
| Karyotype group | |||
| Good | — | — | — |
| Intermediate | 0.6 | .40 | [0.2,1.9] |
| Poor | 1.9 | .09 | [0.9,4.0] |
| Overall likelihood ratio, P | .09 | ||
| Cytopenias | |||
| 0/1 | — | — | — |
| 2/3 | 1.4 | .36 | [0.6,3.1] |
P value from a likelihood ratio test. — indicates not applicable.