Toxicity of chTNT-3/IL-2 WT and IL-2 analog fusion proteins in BALB/c mice treated intravenously for 5 consecutive days
Fusion protein . | 10 μg . | 25 μg . | 50 μg . | 75 μg . | 100 μg . |
|---|---|---|---|---|---|
| chTNT-3/IL-2 WT | 0/5* | 2/5 | 5/5 | 5/5 | 5/5 |
| chTNT-3/Arg38Trp | 0/5 | 0/5 | 0/5 | 2/5 | 5/5 |
| chTNT-3/Asn88Arg | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 |
Fusion protein . | 10 μg . | 25 μg . | 50 μg . | 75 μg . | 100 μg . |
|---|---|---|---|---|---|
| chTNT-3/IL-2 WT | 0/5* | 2/5 | 5/5 | 5/5 | 5/5 |
| chTNT-3/Arg38Trp | 0/5 | 0/5 | 0/5 | 2/5 | 5/5 |
| chTNT-3/Asn88Arg | 0/5 | 0/5 | 0/5 | 0/5 | 0/5 |
Data expressed as number of mice dead over total number injected.