Table 2.

Statistically different genes between Igλ-MM and Igκ-MM

Gene symbol
Gene description
Accession no.
Discriminating score
IGL@  Ig lambda   H14524   -2.74  
ESTs  Unknown   H26676   -2.56  
ESTs  Unknown   H26661   -1.94  
IGL@  Ig lambda   R83196   -1.81  
ESTs  Unknown   H15899   -1.80  
CDSN  Corneodesmosin   W95594   -1.77  
MCP  Membrane cofactor protein (CD46)   H26673   -1.66  
ESTs  Unknown   R83001   -1.63  
IGL@  Ig lambda   H15030   -1.62  
ESTs  Unknown   R74030   -1.33  
ABCD4  ATP-binding cassette, subfamily D, member 4   H51632   -1.22  
SAMHD1  SAM domain and HD domain, 1   H47862   -1.07  
LTBP4*  Latent transforming growth factor-beta-binding protein 4   R73631   -1.02  
ESTs  Unknown   R91051   -1.02  
ESTs  Unknown   R89772   -0.99  
LMNA  LaminA/C   H26659   -0.98  
IGL@  Ig lambda   H41911   -0.95  
ESTs  Unknown   R16095   -0.91  
ZNF361  Zinc finger protein 361   R73795   -0.90  
LTA  Lymphotoxin-alpha   AA910185   -0.81  
RPL4  Ribosomal protein L4   N35801   -0.77  
ESTs  Unknown   N35710   -0.66  
FMO5  Flavin-containing monooxygenase 5   H51750   -0.65  
ESTs  Unknown   R72642   -0.64  
MXI1  Max-interacting protein 1   AA115514   -0.63  
SCN1B  Sodium channel, voltage-gated, type 1, beta subunit   R74526   -0.61  
ARHG  Ras homolog gene family, member G   H45512   -0.58  
NTE  Neuropathy target esterase   H09751   -0.57  
HVEB  Herpesvirus entry mediator B   R73625   -0.56  
AXL  AXL receptor tyrosine kinase   H09737   -0.52  
GAR22  GAS2-related on chromosome 22   R72509   -0.51  
PBX1  Pre-B-cell leukemia transcription factor 1   AA403031   -0.51  
HYAL1  Hyaluronoglucosaminidase 1   W84634   -0.50  
PRKCI  Protein kinase C, iota form   AA062633   0.50  
PLXNB3  Plexin B 3   R41456   0.50  
CTSB  Cathepsin B   H98635   0.51  
CSNK2A2  Casein kinase II, alpha-2   AA099405   0.53  
MMP12  Matrix metalloproteinase 12   R63637   0.54  
ACK1  Human activated p21 cdc42Hs kinase   R44803   0.54  
ESTs  Unknown   AA883518   0.55  
EDN3  Endothelin 3   AA553611   0.58  
ESTs  Unknown   W74500   0.59  
CUL4A  Cullin 4A   AA100650   0.59  
DDR1  Discoidin domain receptor family, member 1   AA574033   0.60  
Mip-1α*  Macrophage inflammatory protein 1-alpha (SCYA3)   W74288   0.64  
ESTs  Unknown   T86845   0.64  
NRID1  Nuclear receptor subfamily 1, group D   R85515   0.66  
UBE4A  Ubiquitination factor E4A   R45238   0.66  
FGR  Gardner-Rasheed feline sarcoma viral oncogene homolog   W81586   0.66  
SIAH2  Seven in absentia, drosophila, homolog of 2   R61685   0.68  
ESTs  Unknown   AA548364   0.71  
TGFβ3*  Transforming growth factor, beta-3   W80655   0.73  
ZNF198  Zinc finger protein 198   N71855   0.81  
TJP2  Tight junction protein 2 (zona occludens 2)   H05082   0.82  
CEP3  cdc42 effector protein 3   R43949   0.86  
ESTs  Unknown   H89735   0.87  
GSTM5  Glutathione S-transferase, mu-5   R40442   0.89  
ESTs  Unknown   N58796   0.91  
IGKC  Ig kappa   AA284839   0.92  
UBE3A  Ubiquitin-protein ligase E3A   AA126792   0.97  
DSG1  Desmoglein 1   W72927   0.97  
RECQL5  RECQ protein-like 5   R32075   1.04  
BPHL  Biphenyl hydrolase-like   AA167197   1.04  
ELAVL4  Embryonic lethal, abnormal vision, drosophila, homolog-like 4   R55730   1.06  
TNFRSF6  Tumor necrosis factor receptor superfamily, member 6 (CD95)   AA031300   1.06  
NR2C1  Nuclear receptor subfamily 2, group C, member 1   H68838   1.10  
SMARCA1  Actin-dependent regulator of chromatin, subfamily A, member 1   AA057875   1.12  
NFE2L3  Nuclear factor erythroid 2-like 3   R43198   1.17  
CYB5  Methemoglobinemia due to deficiency of cytochrome b5   N23249   1.19  
LAMB3  Laminin, beta-3   AA622206   1.19  
SH3GL2  SH3 domain, GRB2-like 2 (endophilin 1)   R20729   1.20  
HSD17B2  17-@beta-hydroxysteroid dehydrogenase II   N23665   1.30  
BMP2*  Bone morphogenetic protein 2   AA114112   1.34  
PRKCABP  PRKCA-binding protein   AA641722   1.54  
HOX11  Homeobox 11   AA007444   1.61  
ESTs  Unknown   N30860   1.66  
ESTs  Unknown   AA826328   1.69  
EXT1  Exostoses, multiple, type 1   R13402   1.70  
ESTs  Unknown   W92915   1.79  
IGKC
 		 Ig kappa
 		 R71916
 		 1.82
 
Gene symbol
Gene description
Accession no.
Discriminating score
IGL@  Ig lambda   H14524   -2.74  
ESTs  Unknown   H26676   -2.56  
ESTs  Unknown   H26661   -1.94  
IGL@  Ig lambda   R83196   -1.81  
ESTs  Unknown   H15899   -1.80  
CDSN  Corneodesmosin   W95594   -1.77  
MCP  Membrane cofactor protein (CD46)   H26673   -1.66  
ESTs  Unknown   R83001   -1.63  
IGL@  Ig lambda   H15030   -1.62  
ESTs  Unknown   R74030   -1.33  
ABCD4  ATP-binding cassette, subfamily D, member 4   H51632   -1.22  
SAMHD1  SAM domain and HD domain, 1   H47862   -1.07  
LTBP4*  Latent transforming growth factor-beta-binding protein 4   R73631   -1.02  
ESTs  Unknown   R91051   -1.02  
ESTs  Unknown   R89772   -0.99  
LMNA  LaminA/C   H26659   -0.98  
IGL@  Ig lambda   H41911   -0.95  
ESTs  Unknown   R16095   -0.91  
ZNF361  Zinc finger protein 361   R73795   -0.90  
LTA  Lymphotoxin-alpha   AA910185   -0.81  
RPL4  Ribosomal protein L4   N35801   -0.77  
ESTs  Unknown   N35710   -0.66  
FMO5  Flavin-containing monooxygenase 5   H51750   -0.65  
ESTs  Unknown   R72642   -0.64  
MXI1  Max-interacting protein 1   AA115514   -0.63  
SCN1B  Sodium channel, voltage-gated, type 1, beta subunit   R74526   -0.61  
ARHG  Ras homolog gene family, member G   H45512   -0.58  
NTE  Neuropathy target esterase   H09751   -0.57  
HVEB  Herpesvirus entry mediator B   R73625   -0.56  
AXL  AXL receptor tyrosine kinase   H09737   -0.52  
GAR22  GAS2-related on chromosome 22   R72509   -0.51  
PBX1  Pre-B-cell leukemia transcription factor 1   AA403031   -0.51  
HYAL1  Hyaluronoglucosaminidase 1   W84634   -0.50  
PRKCI  Protein kinase C, iota form   AA062633   0.50  
PLXNB3  Plexin B 3   R41456   0.50  
CTSB  Cathepsin B   H98635   0.51  
CSNK2A2  Casein kinase II, alpha-2   AA099405   0.53  
MMP12  Matrix metalloproteinase 12   R63637   0.54  
ACK1  Human activated p21 cdc42Hs kinase   R44803   0.54  
ESTs  Unknown   AA883518   0.55  
EDN3  Endothelin 3   AA553611   0.58  
ESTs  Unknown   W74500   0.59  
CUL4A  Cullin 4A   AA100650   0.59  
DDR1  Discoidin domain receptor family, member 1   AA574033   0.60  
Mip-1α*  Macrophage inflammatory protein 1-alpha (SCYA3)   W74288   0.64  
ESTs  Unknown   T86845   0.64  
NRID1  Nuclear receptor subfamily 1, group D   R85515   0.66  
UBE4A  Ubiquitination factor E4A   R45238   0.66  
FGR  Gardner-Rasheed feline sarcoma viral oncogene homolog   W81586   0.66  
SIAH2  Seven in absentia, drosophila, homolog of 2   R61685   0.68  
ESTs  Unknown   AA548364   0.71  
TGFβ3*  Transforming growth factor, beta-3   W80655   0.73  
ZNF198  Zinc finger protein 198   N71855   0.81  
TJP2  Tight junction protein 2 (zona occludens 2)   H05082   0.82  
CEP3  cdc42 effector protein 3   R43949   0.86  
ESTs  Unknown   H89735   0.87  
GSTM5  Glutathione S-transferase, mu-5   R40442   0.89  
ESTs  Unknown   N58796   0.91  
IGKC  Ig kappa   AA284839   0.92  
UBE3A  Ubiquitin-protein ligase E3A   AA126792   0.97  
DSG1  Desmoglein 1   W72927   0.97  
RECQL5  RECQ protein-like 5   R32075   1.04  
BPHL  Biphenyl hydrolase-like   AA167197   1.04  
ELAVL4  Embryonic lethal, abnormal vision, drosophila, homolog-like 4   R55730   1.06  
TNFRSF6  Tumor necrosis factor receptor superfamily, member 6 (CD95)   AA031300   1.06  
NR2C1  Nuclear receptor subfamily 2, group C, member 1   H68838   1.10  
SMARCA1  Actin-dependent regulator of chromatin, subfamily A, member 1   AA057875   1.12  
NFE2L3  Nuclear factor erythroid 2-like 3   R43198   1.17  
CYB5  Methemoglobinemia due to deficiency of cytochrome b5   N23249   1.19  
LAMB3  Laminin, beta-3   AA622206   1.19  
SH3GL2  SH3 domain, GRB2-like 2 (endophilin 1)   R20729   1.20  
HSD17B2  17-@beta-hydroxysteroid dehydrogenase II   N23665   1.30  
BMP2*  Bone morphogenetic protein 2   AA114112   1.34  
PRKCABP  PRKCA-binding protein   AA641722   1.54  
HOX11  Homeobox 11   AA007444   1.61  
ESTs  Unknown   N30860   1.66  
ESTs  Unknown   AA826328   1.69  
EXT1  Exostoses, multiple, type 1   R13402   1.70  
ESTs  Unknown   W92915   1.79  
IGKC
 		 Ig kappa
 		 R71916
 		 1.82
 
*

Genes known to be involved in bone remodeling.

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