Table 1.

Characteristics of patients and cord blood units

Case
Stage
Age, y/sex
Body weight, kg
No. of HLA-A, B, DRB1 mismatches
Cord blood cell dose, × 107/kg
Recipient CMV status
Mo. from diagnosis to transplantation
Blasts in bone marrow before transplantation, %
Cytogenetics*
1   sAML   27/F   43   2 (B, DRB1)   4.06   Positive   101   69.8   Poor  
2   sAML   37/F   51   2 (DRB1, DRB1)   2.3   Positive   7   78.8   Good  
3   sAML   49/F   53   1 (A)   2.13   Negative   4   34.2   Good  
4   sAML   47/F   44   1 (B)   2.09   Positive   37   61.6   Intermediate  
5   sAML   50/M   63   1 (A)   2.5   Positive   9   41   Intermediate  
6   sAML   38/F   45   1 (DRB1)   2.09   Negative   5   86   Good  
7   sAML   20/M   57   2 (B, DRB1)   2.18   Positive   38   34   Poor  
8   RAEB   41/F   44   2 (B, DRB1)   3.1   Positive   60   12   Intermediate  
9   sAML   51/M   59   2 (A, B)   2.43   Positive   28   11.5   Poor  
10   RAEB   36/F   45   2 (A, B)   2.54   Positive   15   8.7   Intermediate  
11   sAML   34/M   56   3 (A, DRB1, DRB1)   2.59   Positive   6   18   Good  
12   sAML   43/M   48   3 (A, B, DRB1)   2.54   Negative   24   3.3   Good  
13
 		 sAML
 		 40/M
 		 68
 		 2 (A, DRB1)
 		 2.37
 		 Positive
 		 7
 		 50.7
 		 Poor
 
Case
Stage
Age, y/sex
Body weight, kg
No. of HLA-A, B, DRB1 mismatches
Cord blood cell dose, × 107/kg
Recipient CMV status
Mo. from diagnosis to transplantation
Blasts in bone marrow before transplantation, %
Cytogenetics*
1   sAML   27/F   43   2 (B, DRB1)   4.06   Positive   101   69.8   Poor  
2   sAML   37/F   51   2 (DRB1, DRB1)   2.3   Positive   7   78.8   Good  
3   sAML   49/F   53   1 (A)   2.13   Negative   4   34.2   Good  
4   sAML   47/F   44   1 (B)   2.09   Positive   37   61.6   Intermediate  
5   sAML   50/M   63   1 (A)   2.5   Positive   9   41   Intermediate  
6   sAML   38/F   45   1 (DRB1)   2.09   Negative   5   86   Good  
7   sAML   20/M   57   2 (B, DRB1)   2.18   Positive   38   34   Poor  
8   RAEB   41/F   44   2 (B, DRB1)   3.1   Positive   60   12   Intermediate  
9   sAML   51/M   59   2 (A, B)   2.43   Positive   28   11.5   Poor  
10   RAEB   36/F   45   2 (A, B)   2.54   Positive   15   8.7   Intermediate  
11   sAML   34/M   56   3 (A, DRB1, DRB1)   2.59   Positive   6   18   Good  
12   sAML   43/M   48   3 (A, B, DRB1)   2.54   Negative   24   3.3   Good  
13
 		 sAML
 		 40/M
 		 68
 		 2 (A, DRB1)
 		 2.37
 		 Positive
 		 7
 		 50.7
 		 Poor
 

CMV indicates cytomegalovirus; sAML, MDS-related secondary acute myeloid leukemia; RAEB, refractory anemia with excess blasts.

*

Cytogenetic analyses were performed immediately before transplantation and according to the International Prognostic Scoring System (IPSS) classification.10 

View Large
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal