End organ involvement in HES patients with and without elevated tryptase levels
Patient group . | Serum tryptase level 12 ng/mL or higher, n = 9 . | Serum tryptase level less than 12 ng/mL, n = 6 . |
|---|---|---|
| Endomyocardial fibrosis | 3 | 0 |
| Pulmonary | 4 | 3 |
| Obstructive | 0 | 3 |
| Restrictive | 4 | 0 |
| Skin | 7 | 6 |
| Pruritus/rash | 6 | 6 |
| Mucosal ulcerations | 3 | 0 |
| Gastrointestinal | 0 | 4 |
| Other* | 0 | 1 |
Patient group . | Serum tryptase level 12 ng/mL or higher, n = 9 . | Serum tryptase level less than 12 ng/mL, n = 6 . |
|---|---|---|
| Endomyocardial fibrosis | 3 | 0 |
| Pulmonary | 4 | 3 |
| Obstructive | 0 | 3 |
| Restrictive | 4 | 0 |
| Skin | 7 | 6 |
| Pruritus/rash | 6 | 6 |
| Mucosal ulcerations | 3 | 0 |
| Gastrointestinal | 0 | 4 |
| Other* | 0 | 1 |
One patient presented with serositis (pleuritis and pericarditis), small vessel vasculitis, and a cerebrovascular accident.