Baseline characteristics and survival
Characteristic . | No. (%) . | Overall survival at 53 months (%) . | P2 . |
|---|---|---|---|
| Total patients | 39 (100) | 60 | — |
| Male sex | 36 (92) | NA | — |
| Median age (range) | 40 (31-57) | — | — |
| Performance status | |||
| ECOG | |||
| 0-1 | 26 (67) | 77 | .004 |
| 2-4 | 13 (33) | 26 | |
| Stage | |||
| I/II | 4/9 (33) | 85 | .04 |
| III/IV | 1/25 (67) | 47 | |
| LDH | |||
| normal | 9 (23) | 67 | .68 |
| less than normal | 30 (77) | 58 | |
| Extranodal sites | |||
| 0-1 | 27 (69) | 72 | .01 |
| 2 or more | 12 (31) | 33 | |
| Central nervous system | |||
| Lymphoma | |||
| Absent | 32 (82) | 70 | .0006 |
| Present | 7 (18) | 14* | |
| Age-adjusted international prognostic index score | |||
| 0/1 | 3/13 (41) | 81 | .03 |
| 2/3 | 13/10 (59) | 44 | |
| Histologic types | |||
| Diffuse large B cell† | 31 (79) | 66 | .22 |
| Burkitt | 7 (18) | 43 | |
| Primary effusion | 1 (3) | ||
| CD4+ cell count per mm3 | |||
| (median) | 198 | NA | |
| 3-100 | 16 (41) | 16 | .0001 |
| 101-1182 | 23 (59) | 87 | |
| HIV viral load log10 | |||
| Median | 4.4 | ||
| Range | 1.69-5.96 | ||
| p53 (n = 27) | |||
| Positive | 16 (59) | 75 | .57 |
| Negative | 11 (41) | 64 | |
| EBV (n = 30) | |||
| Positive | 10 (33) | 44 | .16 |
| Negative | 20 (67) | 71 |
Characteristic . | No. (%) . | Overall survival at 53 months (%) . | P2 . |
|---|---|---|---|
| Total patients | 39 (100) | 60 | — |
| Male sex | 36 (92) | NA | — |
| Median age (range) | 40 (31-57) | — | — |
| Performance status | |||
| ECOG | |||
| 0-1 | 26 (67) | 77 | .004 |
| 2-4 | 13 (33) | 26 | |
| Stage | |||
| I/II | 4/9 (33) | 85 | .04 |
| III/IV | 1/25 (67) | 47 | |
| LDH | |||
| normal | 9 (23) | 67 | .68 |
| less than normal | 30 (77) | 58 | |
| Extranodal sites | |||
| 0-1 | 27 (69) | 72 | .01 |
| 2 or more | 12 (31) | 33 | |
| Central nervous system | |||
| Lymphoma | |||
| Absent | 32 (82) | 70 | .0006 |
| Present | 7 (18) | 14* | |
| Age-adjusted international prognostic index score | |||
| 0/1 | 3/13 (41) | 81 | .03 |
| 2/3 | 13/10 (59) | 44 | |
| Histologic types | |||
| Diffuse large B cell† | 31 (79) | 66 | .22 |
| Burkitt | 7 (18) | 43 | |
| Primary effusion | 1 (3) | ||
| CD4+ cell count per mm3 | |||
| (median) | 198 | NA | |
| 3-100 | 16 (41) | 16 | .0001 |
| 101-1182 | 23 (59) | 87 | |
| HIV viral load log10 | |||
| Median | 4.4 | ||
| Range | 1.69-5.96 | ||
| p53 (n = 27) | |||
| Positive | 16 (59) | 75 | .57 |
| Negative | 11 (41) | 64 | |
| EBV (n = 30) | |||
| Positive | 10 (33) | 44 | .16 |
| Negative | 20 (67) | 71 |